Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 14/20 | 0.53 |
| ▸ | DRD3 | P35462 | 8/20 | 0.53 |
| ▸ | DRD4 | P21917 | 6/20 | 0.53 |
| ▸ | DRD1 | P21728 | 5/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 3/20 | 0.50 |
| ▸ | HTR7 | P34969 | 3/20 | 0.50 |
| ▸ | DRD5 | P21918 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7510149 | 1.00 | DRD2 (0.53) | DRD2DRD3DRD4DRD1CYP1A2 | |
| Hydrochloric Acid SCHEMBL10878787 | 0.91 | DRD2 (0.52) | DRD2DRD3DRD4DRD1CYP1A2 | |
| SCHEMBL10880061 | 0.91 | DRD3 (0.53) | DRD2DRD3DRD4DRD1CYP1A2 | |
| SCHEMBL7521684 | 0.86 | DRD2 (0.62) | DRD2DRD3DRD4DRD1CYP1A2 | |
| SCHEMBL7521679 | 0.86 | DRD2 (0.62) | DRD2DRD3DRD4DRD1CYP1A2 | |
| Hydrochloric Acid SCHEMBL7516146 | 0.85 | DRD2 (0.61) | DRD2DRD3DRD4DRD1CYP1A2 | |
| Hydrochloric Acid SCHEMBL7516152 | 0.85 | DRD2 (0.61) | DRD2DRD3DRD4DRD1CYP1A2 | |
| SCHEMBL22703437 | 0.85 | DRD3 (0.62) | DRD2DRD3DRD4DRD1CYP1A2 | |
| SCHEMBL22694040 | 0.85 | DRD3 (0.62) | DRD2DRD3DRD4DRD1CYP1A2 | |
| SCHEMBL22703442 | 0.81 | DRD3 (0.53) | DRD2DRD3DRD4DRD1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0970042-B1 | 5-HYDROXYMETHYL-2-AMINOTETRALINS AS CARDIOVASCULAR AGENTS | ZAMBON SPA (IT) | 2002-01-09 | — | — | EP | disclosed |