SCHEMBL751015

SCHEMBL751015

NC(=O)C(F)(F)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10638964 0.85
SCHEMBL15993915 0.79
Trifluoroacetamide SCHEMBL20915034 0.79 ALDH1A1 (0.39)
SCHEMBL25877659 0.76 F2 (0.31)
SCHEMBL31272081 0.76 F2 (0.31)
SCHEMBL31272382 0.76 ALDH1A1 (0.30)
SCHEMBL31272417 0.76 ALDH1A1 (0.30)
SCHEMBL31272238 0.76 ALDH1A1 (0.30)
SCHEMBL25877715 0.76 ALDH1A1 (0.30)
SCHEMBL30995902 0.75 ALDH1A1 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230220313-A1 COMPOSITION AND METHOD FOR INACTIVATING A VIRUS RNASSIST LTD. (GB) 2023-07-13 US claimed
EP-4133062-A1 COMPOSITION AND METHOD FOR INACTIVATING A VIRUS Rnassist Limited (GB) 2023-02-15 EP claimed
CN-113583075-B Preparation method of medroxyprogesterone 浙江神洲药业有限公司 2022-05-20 CN claimed
CN-113583075-A Preparation method of medroxyprogesterone 浙江神洲药业有限公司 2021-11-02 CN claimed
CN-111848719-A Efficient and low-pollution preparation method of eplerenone 浙江神洲药业有限公司 2020-10-30 CN claimed
CN-1558898-A Antiviral agent ��Ұ����ҩ��ʽ���� 2004-12-29 CN claimed
EP-1422218-A1 ANTIVIRAL AGENT SHIONOGI & CO., LTD. (JP) 2004-05-26 EP claimed
US-20030055274-A1 Processes for preparation of 9,11-epoxy steroids and intermediates useful therein G.D. SEARLE & COMPANY 2003-03-20 US claimed
EP-1148061-A2 Process for preparation of 9, 11- epoxy steroids and intermediates useful therein G.D. SEARLE & CO. (US) 2001-10-24 EP claimed
EP-0944644-A2 PROCESSES FOR PREPARATION OF 9,11-EPOXY STEROIDS AND INTERMEDIATES USEFUL THEREIN G.D. Searle &amp; Co. (US) 1999-09-29 EP claimed
US-5897940-A Ink jet transparencies XEROX CORPORATION (US) 1999-04-27 US claimed
WO-1998025948-A9 PROCESSES FOR PREPARATION OF 9,11-EPOXY STEROIDS AND INTERMEDIATES USEFUL THEREIN 1998-11-19 WO claimed
WO-1998025948-A2 PROCESSES FOR PREPARATION OF 9,11-EPOXY STEROIDS AND INTERMEDIATES USEFUL THEREIN G.D. SEARLE & CO. (US) 1998-06-18 WO claimed
US-5744273-A Laminatable backing substrates containing fluoro compounds for improved toner flow XEROX CORPORATION (US) 1998-04-28 US claimed
US-5354495-A Homo- or copolymerizable through ethylenic unsaturation NIPPON PAINT CO., LTD. (JP) 1994-10-11 US claimed
US-4935413-A ELASTICITY, ADHESION AND DISPERSIBILITY NIPPON PAINT CO., LTD. (JP) 1990-06-19 US claimed
WO-2025262036-A1 METHOD OF MANUFACTURING A PHARMACEUTICAL COMPOSITION RNASSIST LTD (GB) 2025-12-26 WO disclosed
WO-2024248021-A1 FILM-FORMING COMPOSITION, METHOD FOR PRODUCING SUBSTRATE, AND METHOD FOR PRODUCING FILM-FORMING COMPOSITION セントラル硝子株式会社 2024-12-05 WO disclosed
US-4362728-A Haloguanidine compounds, pharmaceutical compositions and methods of use ICI AMERICAS INC. (US) 1982-12-07 US disclosed
EP-0030092-A1 Guanidine derivatives, processes for their manufacture and pharmaceutical compositions containing them IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1981-06-10 EP disclosed