⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL921584 | 0.80 | — | — | |
| SCHEMBL17533383 | 0.78 | — | — | |
| SCHEMBL2030841 | 0.78 | TAAR1 (0.71) | — | |
| SCHEMBL9816188 | 0.78 | ADRA2A (0.53) | — | |
| SCHEMBL841961 | 0.75 | ADRA2A (0.55) | — | |
| SCHEMBL19435793 | 0.75 | ADRA2A (0.55) | — | |
| SCHEMBL919357 | 0.75 | TAAR1 (0.55) | — | |
| SCHEMBL72881 | 0.75 | — | — | |
| SCHEMBL20146704 | 0.74 | TAAR1 (0.73) | — | |
| SCHEMBL20135772 | 0.74 | TAAR1 (0.73) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112759575-B | Preparation method of clopidogrel hydrogen sulfate and intermediate N- (2-thienylethyl) methylamine thereof | 武汉武药制药有限公司 | 2022-06-07 | — | — | CN | claimed |
| CN-112759575-A | Preparation method of clopidogrel hydrogen sulfate and intermediate N- (2-thienylethyl) methylene thereof | 武汉武药制药有限公司 | 2021-05-07 | — | — | CN | claimed |
| CN-112759575-B | Preparation method of clopidogrel hydrogen sulfate and intermediate N- (2-thienylethyl) methylamine thereof | 武汉武药制药有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-112759575-A | Preparation method of clopidogrel hydrogen sulfate and intermediate N- (2-thienylethyl) methylene thereof | 武汉武药制药有限公司 | 2021-05-07 | — | — | CN | disclosed |
| WO-2012069605-A1 | NOVEL E,E-DIENE COMPOUNDS AND THEIR USE AS MEDICAMENTS AND COSMETICS | DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) | 2012-05-31 | — | — | WO | disclosed |
| EP-2455377-A1 | Synthesis of fentanyl analogs | hameln rds gmbh (DE) | 2012-05-23 | — | — | EP | disclosed |
| US-20120029192-A1 | Pyrazole Derivatives | PFIZER INC | 2012-02-02 | — | — | US | disclosed |
| US-8063044-B2 | Pyrazole derivatives | PFIZER INC. (US) | 2011-11-22 | — | — | US | disclosed |
| US-7799952-B2 | Stereoselective method for the production of (R)-Dimepranol | RATIOPHARM GMBH (DE) | 2010-09-21 | — | — | US | disclosed |
| US-7799952-B2 | Stereoselective method for the production of (R)-Dimepranol | RATIOPHARM GMBH (DE) | 2010-09-21 | — | — | US | disclosed |
| US-7713961-B2 | Substituted 1,2-ethylenediamines, methods for preparing them and uses thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-05-11 | — | — | US | disclosed |
| US-7435728-B2 | Pyrazole derivatives | PFIZER INC (US) | 2008-10-14 | — | — | US | disclosed |
| EP-1737868-B1 | STEREOSELECTIVE METHOD FOR THE PRODUCTION OF CLOPIDOGREL | RATIOPHARM GMBH (DE) | 2008-02-27 | — | — | EP | disclosed |
| US-20070219166-A1 | Stereoselective Method for the Production of Clopidogrel | RATIOPHARM GMBH (DE) | 2007-09-20 | — | — | US | disclosed |
| US-20070219166-A1 | Stereoselective Method for the Production of Clopidogrel | RATIOPHARM GMBH (DE) | 2007-09-20 | — | — | US | disclosed |
| US-7220765-B2 | Derivatives of 2-arylimino-2,3-dihydrothiazoles, their preparation processes and their therapeutic use | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (SCRAS) (FR) | 2007-05-22 | — | — | US | disclosed |
| EP-1226146-A2 | QUINOLINE AND NAPHTHYRIDINE CARBOXYLIC ACID ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2002-07-31 | — | — | EP | disclosed |
| US-20020049223-A1 | Quinoline and naphthyridine carboxylic acid antibacterials | ABBOTT LABORATORIES | 2002-04-25 | — | — | US | disclosed |
| WO-2001032655-A2 | QUINOLINE AND NAPHTHYRIDINE CARBOXYLIC ACID ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2001-05-10 | — | — | WO | disclosed |
| EP-0187390-B1 | NOVEL ALLYLIC AMINES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-08-08 | — | — | EP | disclosed |