Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.58 |
| ▸ | BCL2L1 | Q07817 | 4/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 2/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1133806 | 0.94 | SOS1 (0.64) | SOS1BCL2L1MCL1SMN1; SMN2TSHR | |
| SCHEMBL1462245 | 0.92 | SOS1 (0.62) | SOS1BCL2L1MCL1SMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL28805909 | 0.92 | SOS1 (0.62) | SOS1BCL2L1MCL1SMN1; SMN2TSHR | |
| Diphenylether SCHEMBL27613252 | 0.88 | SMN1; SMN2 (0.73) | SOS1SMN1; SMN2TSHRLMNAHTT | |
| SCHEMBL6090901 | 0.85 | ALDH1A1 (0.58) | SOS1SMN1; SMN2TSHRLMNAHTT | |
| SCHEMBL9249636 | 0.85 | ALDH1A1 (0.58) | SOS1SMN1; SMN2TSHRLMNAHTT | |
| SCHEMBL9452130 | 0.84 | HTT (0.72) | SOS1BCL2L1MCL1SMN1; SMN2TSHR | |
| SCHEMBL21993467 | 0.83 | TSHR (0.71) | SMN1; SMN2TSHRLMNAHTTKMT2A | |
| SCHEMBL34718 | 0.83 | TSHR (0.71) | SMN1; SMN2TSHRLMNAHTTKMT2A | |
| SCHEMBL15849846 | 0.83 | TSHR (0.71) | SMN1; SMN2TSHRLMNAHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165501-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2002-01-02 | — | — | EP | disclosed |
| US-6197770-B1 | ENZYME INHIBITORS; ANTIARTHRITIC AGENTS; BONE DISORDERS | THE PROCTER & GAMBLE CO. | 2001-03-06 | — | — | US | disclosed |
| WO-2000051975-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-08 | — | — | WO | disclosed |