Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7509741 | 1.00 | PKM (0.43) | PKMATMHSD17B10 | |
| SCHEMBL7510796 | 1.00 | PKM (0.43) | PKMATMHSD17B10 | |
| Butane SCHEMBL7508596 | 0.98 | PKM (0.42) | PKMATMHSD17B10 | |
| Methane SCHEMBL7507409 | 0.98 | PKM (0.42) | PKMATMHSD17B10 | |
| Pentane SCHEMBL7506155 | 0.98 | PKM (0.42) | PKMATMHSD17B10 | |
| SCHEMBL6446128 | 0.83 | KMT2A (0.46) | — | |
| SCHEMBL7507085 | 0.82 | PKM (0.68) | PKMATMHSD17B10 | |
| SCHEMBL20223345 | 0.80 | PKM (0.50) | PKMATMHSD17B10 | |
| SCHEMBL7511540 | 0.79 | KMT2A (0.45) | — | |
| SCHEMBL4408230 | 0.78 | KMT2A (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203767-A1 | Heterocyclic-substituted alkylamide acat inhibitors | WARNER-LAMBERT COMPANY (US) | 2002-05-08 | — | — | EP | disclosed |
| EP-0684945-A1 | HETEROCYCLIC-SUBSTITUTED ALKYL AMIDE ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1995-12-06 | — | — | EP | disclosed |
| WO-1994019330-A1 | HETEROCYCLIC-SUBSTITUTED ALKYL AMIDE ACAT INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1994-09-01 | — | — | WO | disclosed |