Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 8/20 | 0.66 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.64 |
| ▸ | MPO | P05164 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | HTR1A | P08908 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | NQO2 | P16083 | 1/20 | 0.64 |
| ▸ | HTR2B | P41595 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | BLM | P54132 | 1/20 | 0.64 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.64 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.64 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7501961 | 0.85 | KMT2A (0.81) | MTNR1AMTNR1BKMT2AMEN1KDM4E | |
| SCHEMBL798104 | 0.85 | MTNR1A (0.72) | MTNR1AMTNR1BKMT2AMEN1KDM4E | |
| SCHEMBL7513866 | 0.82 | KMT2A (0.88) | MTNR1AMTNR1BKMT2AMEN1KDM4E | |
| SCHEMBL5612765 | 0.81 | MTNR1A (0.80) | MTNR1AMTNR1BKMT2AMEN1KDM4E | |
| SCHEMBL29524586 | 0.81 | MTNR1A (0.80) | MTNR1AMTNR1BKMT2AMEN1KDM4E | |
| SCHEMBL16137407 | 0.80 | MTNR1A (0.81) | MTNR1AMTNR1BKMT2AMEN1KDM4E | |
| SCHEMBL7794006 | 0.80 | MTNR1A (1.00) | MTNR1AMTNR1BKMT2AMEN1KDM4E | |
| SCHEMBL7794072 | 0.80 | MTNR1A (0.79) | MTNR1AMTNR1BKMT2AMEN1KDM4E | |
| SCHEMBL19261961 | 0.80 | MTNR1A (0.80) | MTNR1AMTNR1BKMT2AMEN1KDM4E | |
| SCHEMBL5616635 | 0.80 | MTNR1A (0.85) | MTNR1AMTNR1BKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1064284-B1 | HYPNOTIC BETA-CARBOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINAL PRODUCTS | MACEF (FR) | 2002-03-27 | — | — | EP | disclosed |
| US-6048868-A | CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS; ANTIDEPRESSANTS | CEMAF (FR) | 2000-04-11 | — | — | US | disclosed |