Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 5/20 | 0.52 |
| ▸ | DRD2 | P14416 | 5/20 | 0.52 |
| ▸ | DRD3 | P35462 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7505278 | 0.94 | DRD4 (0.59) | DRD4DRD2DRD3TSHRLMNA | |
| SCHEMBL7511059 | 0.89 | DRD4 (0.50) | DRD4DRD2DRD3TSHRABCB1 | |
| SCHEMBL6212093 | 0.87 | DRD2 (0.47) | DRD4DRD2DRD3TSHRABCB1 | |
| SCHEMBL6212018 | 0.86 | DRD4 (0.56) | DRD4DRD2DRD3TSHRLMNA | |
| SCHEMBL7510245 | 0.86 | DRD4 (0.51) | DRD4DRD2DRD3TSHRLMNA | |
| SCHEMBL6212964 | 0.83 | ABCB1 (0.65) | DRD4DRD2DRD3TSHRABCB1 | |
| SCHEMBL7508560 | 0.83 | DRD4 (0.57) | DRD4DRD2DRD3TSHRLMNA | |
| SCHEMBL6211708 | 0.83 | ABCB1 (0.63) | DRD4DRD2DRD3TSHRLMNA | |
| SCHEMBL19852437 | 0.82 | DRD4 (0.76) | DRD4DRD2DRD3TSHRLMNA | |
| SCHEMBL21142445 | 0.82 | DRD4 (0.76) | DRD4DRD2DRD3TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263724-A1 | NOVEL COMPOUNDS | AstraZeneca AB (SE) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001062728-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2001-08-30 | — | — | WO | disclosed |