Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.47 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 4/20 | 0.40 |
| ▸ | DRD4 | P21917 | 4/20 | 0.40 |
| ▸ | DRD3 | P35462 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL500304 | 0.87 | GBA1 (0.49) | GBA1FUCA1ACHESIGMAR1RORC | |
| SCHEMBL500305 | 0.87 | GBA1 (0.49) | GBA1FUCA1ACHESIGMAR1RORC | |
| SCHEMBL500306 | 0.87 | GBA1 (0.49) | GBA1FUCA1ACHESIGMAR1RORC | |
| SCHEMBL14405528 | 0.86 | GBA1 (0.48) | GBA1FUCA1ACHESIGMAR1RORC | |
| SCHEMBL12616743 | 0.86 | GBA1 (0.48) | GBA1FUCA1ACHESIGMAR1RORC | |
| SCHEMBL18487833 | 0.83 | GBA1 (0.46) | GBA1FUCA1ACHESIGMAR1RORC | |
| SCHEMBL12616527 | 0.82 | FUCA1 (0.50) | GBA1FUCA1ACHESIGMAR1RORC | |
| SCHEMBL14302242 | 0.82 | RORC (0.56) | GBA1FUCA1ACHESIGMAR1RORC | |
| SCHEMBL20463841 | 0.82 | FUCA1 (0.50) | GBA1FUCA1ACHESIGMAR1RORC | |
| SCHEMBL12616175 | 0.82 | FUCA1 (0.50) | GBA1FUCA1ACHESIGMAR1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255739-A1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2002-11-13 | — | — | EP | disclosed |
| WO-2001053273-A1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2001-07-26 | — | — | WO | disclosed |