SCHEMBL751071

SCHEMBL751071

O=S(=O)(O)CCSCCS(=O)(=O)O.[NaH].[NaH]

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.43
PTGS1 P23219 1/20 0.43
PDE4A P27815 1/20 0.43
SLC6A6 P31641 1/20 0.43
CYP2C19 P33261 1/20 0.43
BLM P54132 1/20 0.43
APP P05067 1/20 0.39
TDP1 Q9NUW8 2/20 0.30
KMT2A Q03164 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13863427 0.97 LMNA (0.45) LMNAPTGS1PDE4ASLC6A6CYP2C19
SCHEMBL15282771 0.94 LMNA (0.43) LMNAPTGS1PDE4ASLC6A6CYP2C19
SCHEMBL6049114 0.94 LMNA (0.43) LMNAPTGS1PDE4ASLC6A6CYP2C19
SCHEMBL2802548 0.94 LMNA (0.43) LMNAPTGS1PDE4ASLC6A6CYP2C19
SCHEMBL15282759 0.88 APP (0.42) LMNAPTGS1PDE4ASLC6A6CYP2C19
SCHEMBL6049116 0.86 TDP1 (0.53) LMNAPTGS1PDE4ASLC6A6CYP2C19
SCHEMBL10060664 0.84 TDP1 (0.37) LMNAPTGS1PDE4ASLC6A6CYP2C19
SCHEMBL8459073 0.84 TSHR (0.38) LMNAPTGS1PDE4ASLC6A6CYP2C19
SCHEMBL11188669 0.84 PTGS1 (0.36) LMNAPTGS1PDE4ASLC6A6CYP2C19
SCHEMBL565134 0.82 APP (0.48) LMNAPTGS1PDE4ASLC6A6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8449957-B2 Recording medium CANON KABUSHIKI KAISHA (JP) 2013-05-28 US disclosed
US-20120070591-A1 RECORDING MEDIUM CANON KABUSHIKI KAISHA (JP) 2012-03-22 US disclosed
EP-2431189-A2 Recording medium Canon Kabushiki Kaisha (JP) 2012-03-21 EP disclosed