Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.48 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18534563 | 1.00 | CTSK (0.48) | CTSKCTSLCTSBCA1CA2 | |
| SCHEMBL12420756 | 1.00 | CTSK (0.48) | CTSKCTSLCTSBCA1CA2 | |
| SCHEMBL28669035 | 0.98 | CTSK (0.47) | CTSKCTSLCTSBCA1CA2 | |
| SCHEMBL21125085 | 0.98 | CTSK (0.47) | CTSKCTSLCTSBCA1CA2 | |
| SCHEMBL18215140 | 0.98 | CTSK (0.47) | CTSKCTSLCTSBCA1CA2 | |
| Ammonia Solution, Strong SCHEMBL4701521 | 0.98 | CTSK (0.47) | CTSKCTSLCTSBCA1CA2 | |
| SCHEMBL4824903 | 0.98 | CTSK (0.47) | CTSKCTSLCTSBCA1CA2 | |
| SCHEMBL4703911 | 0.98 | CTSK (0.47) | CTSKCTSLCTSBCA1CA2 | |
| SCHEMBL4773114 | 0.88 | CA1 (0.46) | CTSKCTSLCTSBCA1CA2 | |
| SCHEMBL357027 | 0.86 | CTSK (0.49) | CTSKCTSLCTSBCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255739-A1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2002-11-13 | — | — | EP | disclosed |
| WO-2001053273-A1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2001-07-26 | — | — | WO | disclosed |