Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26036272 | 0.86 | KMT2A (0.55) | KMT2ARAB9AFFAR1MAPTHSD17B10 | |
| SCHEMBL26036263 | 0.86 | KMT2A (0.55) | KMT2ARAB9AFFAR1MAPTHSD17B10 | |
| SCHEMBL12154210 | 0.84 | KMT2A (0.59) | KMT2ARAB9AMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL3551022 | 0.76 | KMT2A (0.64) | KMT2ARAB9AMAPTSMN1; SMN2HSD17B10 | |
| SCHEMBL10162103 | 0.76 | ADRB2 (0.63) | KMT2ARAB9ACLK4MAPTTP53 | |
| SCHEMBL12154251 | 0.76 | KMT2A (0.50) | KMT2ARAB9AMAPTTP53NPC1 | |
| SCHEMBL9269967 | 0.75 | KMT2A (0.51) | KMT2ARAB9AMAPTTP53NPC1 | |
| SCHEMBL26036266 | 0.75 | KMT2A (0.45) | KMT2AFFAR1MAPTHSD17B10 | |
| SCHEMBL10936365 | 0.75 | RARB (0.58) | KMT2ARAB9AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL14075281 | 0.74 | KMT2A (0.52) | KMT2ARAB9AMAPTSMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0541081-B1 | Compounds with only a side chain for use in liquid crystal mixtures | AVENTIS RES & TECH GMBH & CO (DE) | 2002-04-10 | — | — | EP | disclosed |
| US-5849216-A | Compounds for use in liquid-crystal mixtures | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-12-15 | — | — | US | disclosed |