SCHEMBL7511142

SCHEMBL7511142

Oc1ccc2c(c1)Oc1ccccc1C2

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.65
MAOB P27338 1/20 0.65
DRD2 P14416 11/20 0.50
DRD1 P21728 11/20 0.50
DRD5 P21918 9/20 0.50
DRD3 P35462 9/20 0.50
DRD4 P21917 8/20 0.50
MAPKAPK2 P49137 1/20 0.46
ESR2 Q92731 1/20 0.45
TRPA1 O75762 1/20 0.45
MEN1 O00255 1/20 0.41
MAPT P10636 1/20 0.41
HPGD P15428 1/20 0.41
CYP2C19 P33261 1/20 0.41
HTT P42858 1/20 0.41
RECQL P46063 1/20 0.41
BLM P54132 1/20 0.41
SMAD3 P84022 1/20 0.41
KMT2A Q03164 1/20 0.41
PRMT1 Q99873 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30578750 1.00 MAOA (0.65) MAOAMAOBDRD2DRD1DRD5
SCHEMBL14041086 0.91 MAOA (0.53) MAOAMAOBDRD2DRD1DRD5
SCHEMBL30534978 0.90 ESR2 (0.52) MAOAMAOBDRD2DRD1DRD5
SCHEMBL3274879 0.90 ESR2 (0.52) MAOAMAOBDRD2DRD1DRD5
SCHEMBL2530756 0.89 MAOA (0.65) MAOAMAOBDRD2DRD1DRD5
SCHEMBL8168164 0.86 MAPKAPK2 (0.47) MAOAMAOBDRD2DRD1DRD5
Xanthene SCHEMBL27661782 0.82 MAOA (0.74) MAOAMAOBDRD2DRD1DRD5
Xanthene SCHEMBL3275202 0.82 MAOA (0.74) MAOAMAOBDRD2DRD1DRD5
SCHEMBL9455528 0.81 MAOA (0.81) MAOAMAOBMAPKAPK2ACSL1
Xanthene SCHEMBL29378346 0.81 MAOA (1.00) MAOAMAOBMAPKAPK2ACSL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122011253-A Sieber resin and preparation method and application thereof 江苏海普功能材料有限公司 2026-05-12 CN disclosed
CN-119350285-A Anthracene skeleton compound and photoinitiator application thereof 湖北兴福电子材料股份有限公司 2025-01-24 CN disclosed
CN-119350286-A A series of multi-benzene ring photoinitiators and photoinitiator application thereof 湖北兴福电子材料股份有限公司 2025-01-24 CN disclosed
CN-116803999-A Preparation method of 3-hydroxy-9H-xanthen-9-one 安徽昊帆生物有限公司 2023-09-26 CN disclosed
US-20230159484-A1 FLUORESCENT DYES HAVING HIGH STOKES SHIFT, ON THE BASIS OF BRIDGED BENZOPYRYLIUM SALTS DYOMICS GMBH (DE) 2023-05-25 US disclosed
EP-3144315-B1 ENZYME-SPECIFIC FLUORESCENT COMPOUND CAPABLE OF BEING RETAINED IN CELLS UNIV TOKYO (JP) 2022-07-06 EP disclosed
CN-113473860-A 1, 3, 4-oxadiazoles and derivatives thereof as novel antifungal agents 拜耳公司 2021-10-01 CN disclosed
CN-106459125-B The Intracellular retention fluorescent chemicals of enzyme spcificity 国立大学法人东京大学 2019-05-07 CN disclosed
CN-109311980-A G protein-coupled receptor (GPCR) modulation by emilienone (IMIPRIDONES) 昂克希尔迪克斯有限公司 2019-02-05 CN disclosed
CN-104263816-B Double label method for measuring cell Proliferation 生命技术公司 2018-10-19 CN disclosed
CN-103735682-B A kind of medicine that is used for the treatment of allergic dermatitis and preparation method thereof ZHOU WENWU (CN) 2016-05-18 CN disclosed
CN-103735682-A Drug for treating allergic dermatitis and preparation method thereof ZHOU WENWU 2014-04-23 CN disclosed
WO-2008021926-A2 MODULATORS OF GLUCOCORTICOID RECEPTOR, AND/OR AP-1, AND/OR NF-KB ACTIVITY AND USE THEREOF BRISTOL-MYERS SQUIBB COMPANY (US) 2008-02-21 WO disclosed
EP-1119554-A4 XANTHAN-ESTER AND ACRIDAN SUBSTRATES FOR HORSERADISH PEROXIDASE TROPIX INC (US) 2002-05-08 EP disclosed
EP-1119554-A1 XANTHAN-ESTER AND ACRIDAN SUBSTRATES FOR HORSERADISH PEROXIDASE TROPIX, INC. (US) 2001-08-01 EP disclosed
US-6162610-A Xanthan-ester and acridan substrates for horseradish peroxidase TROPIX, INC. (US) 2000-12-19 US disclosed
WO-2000015618-A1 XANTHAN-ESTER AND ACRIDAN SUBSTRATES FOR HORSERADISH PEROXIDASE TROPIX, INC. (US) 2000-03-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159484-A1 FLUORESCENT DYES HAVING HIGH STOKES SHIFT, ON THE BASIS OF BRIDGED BENZOPYRYLIUM SALTS SUN2, IK, BRD7 MAOA 4200/4885MAOB 3073/4885DRD2 521/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.