Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | GMNN | O75496 | 1/20 | 0.53 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8843405 | 0.98 | GSR (0.64) | GSRALDH1A1GAATSHRLMNA | |
| SCHEMBL28292868 | 0.85 | GSR (0.65) | GSRALDH1A1GAATSHRLMNA | |
| SCHEMBL19937119 | 0.85 | GSR (0.76) | GSRALDH1A1GAATSHRLMNA | |
| SCHEMBL5791663 | 0.83 | GSR (0.62) | GSRALDH1A1GAATSHRLMNA | |
| SCHEMBL39559 | 0.82 | ALDH1A1 (0.63) | GSRALDH1A1GAATSHRLMNA | |
| SCHEMBL11775795 | 0.82 | GSR (0.61) | GSRALDH1A1GAATSHRLMNA | |
| SCHEMBL9124297 | 0.82 | GSR (0.61) | GSRALDH1A1GAATSHRLMNA | |
| SCHEMBL526641 | 0.80 | ALDH1A1 (0.61) | GSRALDH1A1GAATSHRLMNA | |
| Hydrochloric Acid SCHEMBL8940929 | 0.80 | GSR (0.62) | GSRALDH1A1GAATSHRLMNA | |
| SCHEMBL16104894 | 0.80 | GSR (0.59) | GSRALDH1A1GAATSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633283-A | Method for treating multiple sclerosis | ELI LILLY AND COMPANY (US) | 1997-05-27 | — | — | US | claimed |
| US-5552439-A | AMINOPHENOL DERIVATIVES | ELI LILLY AND COMPANY (US) | 1996-09-03 | — | — | US | claimed |
| WO-1996022769-A1 | METHOD FOR TREATING MULTIPLE SCLEROSIS | ELI LILLY AND COMPANY (US) | 1996-08-01 | — | — | WO | claimed |
| EP-0722723-A2 | Phenol derivatives for treating multiple sclerosis | ELI LILLY AND COMPANY (US) | 1996-07-24 | — | — | EP | claimed |
| EP-0680755-A1 | Method for treating inflammation, ischemia-induced cell damage and muscular dystrophy | ELI LILLY AND COMPANY (US) | 1995-11-08 | — | — | EP | claimed |
| EP-0474403-B1 | Method of treating inflammatory bowel disease | LILLY CO ELI (US) | 1995-05-10 | — | — | EP | claimed |
| US-5393786-A | Administering certain phenolic compounds | ELI LILLY AND COMPANY (US) | 1995-02-28 | — | — | US | claimed |
| US-5281623-A | Administering amino substituted phenolic derivatives as antiinflammatory or antiarthritic agents | ELI LILLY AND COMPANY (US) | 1994-01-25 | — | — | US | claimed |
| EP-0476846-A2 | Method for treating imflammation, ischemia-induced cell damage and muscular dystrophy | ELI LILLY AND COMPANY (US) | 1992-03-25 | — | — | EP | claimed |
| EP-0474403-A1 | Method of treating inflammatory bowel disease | ELI LILLY AND COMPANY (US) | 1992-03-11 | — | — | EP | claimed |
| US-4480133-A | Chemical process | ETHYL CORPORATION (US) | 1984-10-30 | — | — | US | claimed |
| EP-0753521-B1 | Process for distilling crude acrylic silane solution | CHISSO CORP (JP) | 2002-01-02 | — | — | EP | disclosed |
| US-5824195-A | USING N-NITROSOPHENYLHYDROXYLAMINE SALT AND/OR COPPER DIALKYLDITHIOCARBAMATE SYNERGISTIC MIXTURE AS POLYMERIZATION INHIBITORS | CHISSO CORPORATION (JP) | 1998-10-20 | — | — | US | disclosed |
| US-5747429-A | SILICONE OIL | TONEN CORPORATION (JP) | 1998-05-05 | — | — | US | disclosed |
| US-5633283-A | Method for treating multiple sclerosis | ELI LILLY AND COMPANY (US) | 1997-05-27 | — | — | US | disclosed |
| EP-0223149-A1 | Heat resistant chloroprene copolymers | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-05-27 | — | — | EP | disclosed |
| US-4605705-A | DIISOPROPYL XANTHOGEN DISULFIDE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-08-12 | — | — | US | disclosed |
| EP-0175245-A2 | Heat resistant sulfur-modified polychloroprene copolymers | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-03-26 | — | — | EP | disclosed |
| US-4480133-A | Chemical process | ETHYL CORPORATION (US) | 1984-10-30 | — | — | US | disclosed |
| US-4124754-A | POLYMERIZATION OF CHLOROPRENE IN THE PRESENCE OF SULFUR | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-11-07 | — | — | US | disclosed |