Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5204904 | 0.84 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL7491749 | 0.81 | PTGS2 (0.81) | PTGS2PTGS1 | |
| SCHEMBL8077136 | 0.80 | PTGS2 (0.66) | PTGS2PTGS1 | |
| SCHEMBL5208687 | 0.80 | PTGS2 (0.70) | PTGS2PTGS1 | |
| SCHEMBL7482159 | 0.80 | PTGS2 (0.74) | PTGS2PTGS1 | |
| SCHEMBL5208760 | 0.73 | PTGS2 (0.80) | PTGS2PTGS1 | |
| SCHEMBL8098676 | 0.72 | PTGS2 (0.67) | PTGS2PTGS1 | |
| SCHEMBL5204814 | 0.70 | PTGS2 (0.74) | PTGS2PTGS1 | |
| SCHEMBL5204886 | 0.69 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL7001779 | 0.68 | PTGS2 (0.54) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863891-B1 | (METHYLSULFONYL)PHENYL-2-(5H)-FURANONES AS COX-2 INHIBITORS | MERCK FROSST CANADA INC (CA) | 2002-12-11 | — | — | EP | disclosed |