Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3718331 | 0.79 | SMN1; SMN2 (0.43) | NPC1GAAMEN1KMT2ASLC1A5 | |
| SCHEMBL359159 | 0.79 | SMN1; SMN2 (0.43) | NPC1GAAMEN1KMT2ASLC1A5 | |
| Hydrochloric Acid SCHEMBL9641232 | 0.78 | SMN1; SMN2 (0.42) | NPC1GAAMEN1KMT2ASLC1A5 | |
| Benzene SCHEMBL27553763 | 0.77 | GAA (0.53) | NPC1GAAMEN1KMT2AHSD17B10 | |
| SCHEMBL41618 | 0.77 | GAA (0.53) | NPC1GAAMEN1KMT2AHSD17B10 | |
| SCHEMBL41619 | 0.77 | GAA (0.53) | NPC1GAAMEN1KMT2AHSD17B10 | |
| SCHEMBL199861 | 0.77 | GAA (0.53) | NPC1GAAMEN1KMT2AHSD17B10 | |
| Hydrochloric Acid SCHEMBL11389456 | 0.75 | GAA (0.51) | NPC1GAAMEN1KMT2AHSD17B10 | |
| Hydrochloric Acid SCHEMBL9474549 | 0.75 | GAA (0.51) | NPC1GAAMEN1KMT2AHSD17B10 | |
| Glycine SCHEMBL28074279 | 0.72 | ALDH1A1 (0.46) | NPC1GAAMEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6495314-B1 | PEPTIDE LADDER LIBRARIES CORRESPONDING TO A PROTEIN, PROTEIN FRAGMENT, OR OTHER BIOACTIVE PEPTIDE AND TO THE USE OF PEPTIDE LADDER LIBRARIES FOR OBTAINING A PROTEIN SIGNATURE ANALYSIS | THE SCRIPPS RESEARCH INSTITUTE | 2002-12-17 | — | — | US | claimed |