Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CFD | P00746 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL749251 | 0.83 | KCNH2 (0.52) | MEN1KMT2AHCRTR1HCRTR2ALDH1A1 | |
| SCHEMBL2709266 | 0.80 | KCNH2 (0.56) | MEN1KMT2AALDH1A1GAAKCNH2 | |
| SCHEMBL205885 | 0.80 | KCNH2 (0.56) | MEN1KMT2AALDH1A1GAAKCNH2 | |
| SCHEMBL9977313 | 0.80 | KCNH2 (0.56) | MEN1KMT2AALDH1A1GAAKCNH2 | |
| SCHEMBL14334610 | 0.79 | ALDH1A1 (0.43) | MEN1KMT2AHCRTR1HCRTR2ALDH1A1 | |
| SCHEMBL13070602 | 0.76 | HCRTR1 (0.51) | KMT2AHCRTR1HCRTR2ALDH1A1GAA | |
| SCHEMBL2709309 | 0.76 | NPC1 (0.59) | MEN1KMT2AHCRTR1HCRTR2ALDH1A1 | |
| SCHEMBL204222 | 0.76 | NPC1 (0.59) | MEN1KMT2AHCRTR1HCRTR2ALDH1A1 | |
| SCHEMBL14334919 | 0.74 | CYP3A4 (0.61) | KCNH2CYP3A4CYP2D6CYP2C9CYP1A2 | |
| SCHEMBL14334765 | 0.73 | KCNH2 (0.41) | MEN1KMT2AALDH1A1KCNH2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430014-A1 | ANTIVIRAL COMPOUNDS | Gilead Sciences, Inc. (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010132601-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2010-11-18 | — | — | WO | disclosed |