Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.44 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | CTRC | Q99895 | 3/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31176573 | 0.77 | BCL2 (0.54) | CALM1BCL2BCL2L1HTR2AALOX5 | |
| SCHEMBL9408084 | 0.77 | CALM1 (0.46) | CALM1BCL2BCL2L1HTR2ACTRC | |
| SCHEMBL9366916 | 0.75 | CALM1 (0.44) | CALM1BCL2BCL2L1HTR2ACTRC | |
| SCHEMBL25349664 | 0.75 | GAA (0.45) | CALM1BCL2BCL2L1HTR2ACTRC | |
| SCHEMBL27660492 | 0.73 | CALM1 (0.42) | CALM1BCL2BCL2L1HTR2ACTRC | |
| SCHEMBL10766018 | 0.72 | TP53 (0.43) | CALM1BCL2BCL2L1HTR2ACTRC | |
| SCHEMBL8823840 | 0.72 | KMT2A (0.60) | CALM1BCL2BCL2L1KMT2AHSD17B10 | |
| SCHEMBL10524083 | 0.72 | BCL2 (0.44) | CALM1BCL2BCL2L1HTR2ACTRC | |
| SCHEMBL6751023 | 0.71 | CALM1 (0.44) | CALM1BCL2BCL2L1HTR2ACYP3A4 | |
| SCHEMBL972711 | 0.69 | CALM1 (0.69) | CALM1BCL2BCL2L1HTR2AALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754696-B1 | Unsymmetric diphosphine monoxide compounds and a process for preparing diphosphine compounds | TAKASAGO PERFUMERY CO LTD (JP) | 2002-01-16 | — | — | EP | disclosed |
| US-5808162-A | Chiral unsymmetric diphosphine compound and transition metal complex containing the same as ligand | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1998-09-15 | — | — | US | disclosed |
| EP-0754696-A1 | Chiral unsymmetric diphosphine compounds and transition metal complexes containing them as ligands | Takasago International Corporation (JP) | 1997-01-22 | — | — | EP | disclosed |
| EP-0317259-A2 | Heterocyclic insecticides | ICI AMERICAS INC. (US) | 1989-05-24 | — | — | EP | disclosed |