Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8953687 | 1.00 | CNR2 (0.47) | CNR2CYP3A4ALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL8953693 | 0.85 | PPARA (0.43) | CNR2CYP3A4ALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL8953404 | 0.82 | MEN1 (0.52) | CNR2CYP3A4ALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL7513061 | 0.82 | MEN1 (0.52) | CNR2CYP3A4ALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL14496299 | 0.79 | ALDH1A1 (0.60) | CNR2ALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL846128 | 0.78 | ALDH1A1 (0.57) | CNR2ALDH1A1SMN1; SMN2HIF1ALMNA | |
| SCHEMBL15212627 | 0.77 | NPC1 (0.48) | CNR2ALDH1A1KDM4EGPR84FFAR1 | |
| SCHEMBL6656017 | 0.76 | PPARA (0.48) | CNR2 | |
| SCHEMBL12677177 | 0.76 | CNR2 (0.46) | CNR2KCNH2 | |
| SCHEMBL1815516 | 0.76 | CNR2 (0.46) | CNR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634408-B1 | DEPSIPEPTIDE DERIVATIVE, PRODUCTION THEREOF AND USE THEREOF | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-01-02 | — | — | EP | disclosed |
| EP-0634408-A1 | DEPSIPEPTIDE DERIVATIVE, PRODUCTION THEREOF AND USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-01-18 | — | — | EP | disclosed |