SCHEMBL7512291

SCHEMBL7512291

C1=CCCCCCCCNCCCCCCC1

nearest known ligand 0.60

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.60
CXCR4 P61073 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HIF1A Q16665 1/20 0.31
MAPT P10636 1/20 0.31
PDE4A P27815 1/20 0.31
KDR P35968 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25826376 1.00 ALDH1A1 (0.60) ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT
Cyclooctene SCHEMBL27218566 1.00 ALDH1A1 (0.60) ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT
SCHEMBL7512710 1.00 ALDH1A1 (0.60) ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT
SCHEMBL7512282 1.00 ALDH1A1 (0.60) ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT
Piperidine SCHEMBL22115426 1.00 ALDH1A1 (0.60) ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT
SCHEMBL7512708 1.00 ALDH1A1 (0.60) ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT
Cyclohexene SCHEMBL10503982 1.00 ALDH1A1 (0.60) ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT
SCHEMBL18710391 1.00 ALDH1A1 (0.60) ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT
SCHEMBL22854438 1.00 ALDH1A1 (0.60) ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT
SCHEMBL27406382 1.00 ALDH1A1 (0.60) ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6359075-B1 POLYMERIZING VINYL AROMATIC MONOMER IN HYDROCARBON SOLVENT IN PRESENCE OF ANIONIC CATALYST TO FORM LIVING POLYMER; ADDING CONJUGATED DIENE TO COPOLYMERIZE, ADDING CHAIN TRANSFER AGENT, ADDING CONJUGATED DIENE, VINYL AROMATIC MONOMER BRIDGESTONE/FIRESTONE, INC. 2002-03-19 US claimed
EP-0709408-B1 Amine containing polymers and products therefrom BRIDGESTONE CORP (JP) 2001-08-22 EP claimed
US-6025450-A CONJUGATED DIENE AND/OR VINYLAROMATIC (CO)POLYMER FUNCTIONALIZED WITH CYCLIC AMINE; TIRES; NARROW MOLECULAR WEIGHT DISTRIBUTION; HYSTERESIS-FREE BRIDGESTONE CORPORATION (JP) 2000-02-15 US claimed
US-5674798-A LITHIUM AMINE COMPOUND AND AN ALKALI METAL ORGANIC COMPOUND BRIDGESTONE CORPORATION (JP) 1997-10-07 US claimed
US-5643848-A POLYMERIZATION CATALYSTS OF LITHIUM COMPOUNDS WITH AMINE COMPOUNDS BRIDGESTONE CORPORATION (JP) 1997-07-01 US claimed
US-5616704-A SOLUBLE IN ACYCLIC ALKANE SOLVENTS BRIDGESTONE CORPORATION (JP) 1997-04-01 US claimed
EP-0741148-A1 Soluble anionic polymerization initiators and products therefrom BRIDGESTONE CORPORATION (JP) 1996-11-06 EP claimed
US-5552473-A Functionalized polymer and rubber compositions produced from solubilized anionic polymerization initiators BRIDGESTONE CORPORATION (JP) 1996-09-03 US claimed
EP-0718321-A1 Anionic polymerization initiators and reduced hysteresis products therefrom BRIDGESTONE CORPORATION (JP) 1996-06-26 EP claimed
EP-0709408-A1 Amine containing polymers and products therefrom BRIDGESTONE CORPORATION (JP) 1996-05-01 EP claimed
EP-0626278-A1 Solubilized anionic polymerization initiators and products therefrom BRIDGESTONE CORPORATION (JP) 1994-11-30 EP claimed
US-20250066591-A1 RUBBER FORMULATIONS COMPRISING FUNCTIONALIZED CONJUGATED DIENE POLYMER, NATURAL RUBBER, AND REINFORCING FILLER BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2025-02-27 US disclosed
WO-2025028543-A1 TIRE RUBBER COMPOSITION, TIRE VULCANIZED RUBBER, TREAD RUBBER, AND TIRE 株式会社ブリヂストン 2025-02-06 WO disclosed
EP-4457284-A1 RUBBER FORMULATIONS COMPRISING FUNCTIONALIZED CONJUGATED DIENE POLYMER, NATURAL RUBBER, AND REINFORCING FILLER Bridgestone Corporation (JP) 2024-11-06 EP disclosed
CN-118574883-A Rubber formulation comprising functionalized conjugated diene polymer, natural rubber and reinforcing filler 株式会社普利司通 2024-08-30 CN disclosed
US-5552473-A Functionalized polymer and rubber compositions produced from solubilized anionic polymerization initiators BRIDGESTONE CORPORATION (JP) 1996-09-03 US disclosed
US-5552499-A Process of preparing reduced hysteresis products using anionic polymerization initiators BRIDGESTONE CORPORATION (JP) 1996-09-03 US disclosed
EP-0718321-A1 Anionic polymerization initiators and reduced hysteresis products therefrom BRIDGESTONE CORPORATION (JP) 1996-06-26 EP disclosed
EP-0709408-A1 Amine containing polymers and products therefrom BRIDGESTONE CORPORATION (JP) 1996-05-01 EP disclosed
EP-0626278-A1 Solubilized anionic polymerization initiators and products therefrom BRIDGESTONE CORPORATION (JP) 1994-11-30 EP disclosed