Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 6/20 | 0.50 |
| ▸ | TPH1 | P17752 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.35 |
| ▸ | FAP | Q12884 | 1/20 | 0.35 |
| ▸ | MC3R | P41968 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | CCR4 | P51679 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6077661 | 0.99 | F2 (0.49) | F2TPH1ACENAMPTHSD11B1 | |
| Hydrochloric Acid SCHEMBL6079169 | 0.89 | F2 (0.59) | F2TPH1ACENPSR1DPP4 | |
| SCHEMBL6078139 | 0.83 | F2 (0.61) | F2TPH1MC3R | |
| SCHEMBL7512500 | 0.80 | F2 (0.61) | F2DPP4DPP8DPP9DPP7 | |
| Hydrochloric Acid SCHEMBL6077658 | 0.79 | F2 (0.60) | F2ACEDPP4DPP8DPP9 | |
| SCHEMBL6078129 | 0.76 | F2 (0.60) | F2TPH1ACENPSR1 | |
| SCHEMBL7513994 | 0.76 | F2 (0.60) | F2TPH1ACENPSR1 | |
| Hydrochloric Acid SCHEMBL6077070 | 0.75 | F2 (0.59) | F2TPH1ACENPSR1 | |
| SCHEMBL7102501 | 0.75 | F2 (0.49) | F2ACENPSR1DPP4DPP8 | |
| SCHEMBL7107001 | 0.75 | CCR4 (0.49) | F2ACENPSR1DPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064559-A2 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2002-08-22 | — | — | WO | disclosed |