Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.48 |
| ▸ | CCR4 | P51679 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.43 |
| ▸ | FAP | Q12884 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7101554 | 0.94 | F2 (0.48) | F2NPSR1SPHK1CCR4ACE | |
| SCHEMBL7107001 | 0.92 | CCR4 (0.49) | F2NPSR1SPHK1CCR4ACE | |
| SCHEMBL7148741 | 0.88 | F2 (0.61) | F2NPSR1SPHK1CCR4ACE | |
| Hydrochloric Acid SCHEMBL7147488 | 0.87 | F2 (0.63) | F2NPSR1SPHK1CCR4ACE | |
| SCHEMBL6920901 | 0.85 | F2 (0.50) | F2 | |
| SCHEMBL7102911 | 0.84 | F2 (0.53) | F2NPSR1SPHK1CCR4ACE | |
| Trifluoroacetic Acid SCHEMBL6925104 | 0.84 | ACE (0.43) | F2NPSR1CCR4ACEOPRK1 | |
| Hydrochloric Acid SCHEMBL6919984 | 0.84 | F2 (0.51) | F2ACE | |
| Hydrochloric Acid SCHEMBL6920199 | 0.84 | ACE (0.46) | F2NPSR1CCR4ACEOPRK1 | |
| SCHEMBL7104974 | 0.82 | ALDH1A1 (0.50) | F2NPSR1ACEDPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672658-B1 | Antithrombotic agents | ASTRAZENECA AB (SE) | 2003-09-17 | — | — | EP | claimed |