SCHEMBL751257

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL754386	0.90	PDE3B (0.38)	MTNR1AMTNR1BNPSR1CNR2GPR55
	SCHEMBL18531663	0.89	MAPK14 (0.44)	MTNR1AMTNR1BNPSR1CNR2GPR55
	SCHEMBL753008	0.84	NPSR1 (0.35)	MTNR1AMTNR1BNPSR1CNR2GPR55
	SCHEMBL753007	0.83	MAPK14 (0.35)	MTNR1AMTNR1BNPSR1CNR2GPR55
	SCHEMBL753713	0.82	MEN1 (0.43)	NPSR1CNR2GPR55MAPK14CNR1
	SCHEMBL753309	0.81	CNR2 (0.40)	CNR2GPR55CNR1MAOB
	SCHEMBL765758	0.78	CNR2 (0.37)	NPSR1CNR2GPR55MAPK14CNR1
	SCHEMBL755219	0.77	CNR2 (0.44)	NPSR1CNR2GPR55PDE3BPDE3A
	SCHEMBL755038	0.76	POLB (0.40)	CNR2GPR55PDE3BPDE3AKMT2A
	SCHEMBL10290270	0.74	CNR2 (0.39)	NPSR1CNR2GPR55CNR1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.