Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL754386 | 0.89 | PDE3B (0.38) | MAPK14HSP90AA1HSP90B1LMNANPSR1 | |
| SCHEMBL751257 | 0.89 | MTNR1A (0.38) | MAPK14HSP90AA1HSP90B1NPSR1MTNR1A | |
| SCHEMBL753007 | 0.87 | MAPK14 (0.35) | MAPK14HSP90AA1HSP90B1POLBLMNA | |
| SCHEMBL753008 | 0.85 | NPSR1 (0.35) | MAPK14HSP90AA1HSP90B1NPSR1MTNR1A | |
| SCHEMBL18531653 | 0.81 | MAPK14 (0.47) | MAPK14HSP90AA1HSP90B1POLBLMNA | |
| SCHEMBL18531596 | 0.73 | CNR1 (0.45) | HSP90AA1HSP90B1POLBLMNANPSR1 | |
| SCHEMBL18531595 | 0.72 | CNR2 (0.38) | MAPK14HSP90AA1HSP90B1POLBLMNA | |
| SCHEMBL18531597 | 0.71 | HSP90AA1 (0.37) | MAPK14HSP90AA1HSP90B1POLBLMNA | |
| SCHEMBL753713 | 0.70 | MEN1 (0.43) | MAPK14NPSR1HTTCNR2GPR55 | |
| SCHEMBL2484219 | 0.70 | ALDH1A1 (0.39) | POLBLMNAHTTCNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9572813-B2 | Antiviral agent | SHIONOGI & CO., LTD. (JP) | 2017-02-21 | — | — | US | disclosed |