SCHEMBL75127

SCHEMBL75127

C=CC(=O)Oc1ccc(-c2ncc(-c3ccc(CCCCCCCC)cc3)cn2)c(F)c1

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
THRB P10828 7/20 0.57
RARB P10826 10/20 0.50
RARA P10276 2/20 0.45
RARG P13631 1/20 0.45
THRA P10827 5/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
MAPT P10636 3/20 0.42
ALDH1A1 P00352 2/20 0.42
MTOR P42345 1/20 0.42
PLA2G4A P47712 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
KDM4E B2RXH2 1/20 0.41
USP2 O75604 1/20 0.41
GAA P10253 1/20 0.41
HPGD P15428 1/20 0.41
RAB9A P51151 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12306158 0.92 THRB (0.57) THRBRARBRARARARGTHRA
SCHEMBL16187781 0.84 RARB (0.52) RARBRARARARGMEN1KMT2A
SCHEMBL16187780 0.84 RARB (0.52) RARBRARARARGMEN1KMT2A
SCHEMBL18590717 0.84 RARB (0.52) RARBRARARARGMEN1KMT2A
SCHEMBL8984168 0.84 RARB (0.52) RARBRARARARGMEN1KMT2A
SCHEMBL7094260 0.82 RARB (0.46) THRBRARBRARARARGTHRA
SCHEMBL10548988 0.81 MAPT (0.53) THRBRARBRARARARGTHRA
SCHEMBL10554182 0.81 MAPT (0.53) THRBRARBRARARARGTHRA
SCHEMBL10551945 0.81 MAPT (0.53) THRBRARBRARARARGTHRA
SCHEMBL10550450 0.81 MAPT (0.53) THRBRARBRARARARGTHRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8992796-B2 Polymerizable liquid crystal composition DIC CORPORATION (JP) 2015-03-31 US disclosed
US-8139189-B2 Liquid crystal display having particular oblique vapor deposition-alignment layer with ferroelectric liquid crystal DAI NIPPON PRINTING CO., LTD. (JP) 2012-03-20 US disclosed
US-20120056129-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION DIC CORPORATION (JP) 2012-03-08 US disclosed
US-8130358-B2 Liquid crystal display DAI NIPPON PRINTING CO., LTD. (JP) 2012-03-06 US disclosed
US-8009266-B2 Process for producing liquid crystal display DAI NIPPON PRINTING CO., LTD. (JP) 2011-08-30 US disclosed
US-7910021-B2 Polymerizable optical active compound and polymerizable composition containing the same ADEKA CORPORATION (JP) 2011-03-22 US disclosed
US-7892449-B2 Liquid crystal display and manufacturing method of same DAI NIPPON PRINTING CO., LTD. (JP) 2011-02-22 US disclosed
US-7871540-B2 Polymerizable liquid crystal composition DIC CORPORATION (JP) 2011-01-18 US disclosed
US-7812905-B2 Liquid crystal display device and manufacturing method thereof HITACHI DISPLAYS, LTD. (JP) 2010-10-12 US disclosed
US-7777847-B2 Liquid crystal display and manufacturing method of the same DAI NIPPON PRINTING CO., LTD. (JP) 2010-08-17 US disclosed
US-20100060844-A1 PROCESS FOR PRODUCING LIQUID CRYSTAL DISPLAY DAI NIPPON PRINTING CO., LTD. (JP) 2010-03-11 US disclosed
US-20100053525-A1 LIQUID CRYSTAL DISPLAY DAI NIPPON PRINTING CO., LTD. (JP) 2010-03-04 US disclosed
US-20100032620-A1 POLYMERIZABLE OPTICAL ACTIVE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING THE SAME ADEKA CORPORATION (JP) 2010-02-11 US disclosed
US-20100007832-A1 LIQUID CRYSTAL DISPLAY DAI NIPPON PRINTING CO., LTD. (JP) 2010-01-14 US disclosed
US-7570331-B2 Liquid crystal display DAI NIPPON PRINTING CO., LTD. (JP) 2009-08-04 US disclosed
US-7499135-B2 Liquid crystal display DAI NIPPON PRINTING CO., LTD. (JP) 2009-03-03 US disclosed
US-20090050844-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION DIC CORPORATION (JP) 2009-02-26 US disclosed
US-20080291377-A1 Liquid Crystal Display Device and Manufacturing Method Thereof HITACHI DISPLAYS, LTD. (JP) 2008-11-27 US disclosed
US-20080074588-A1 LIQUID CRYSTAL DISPLAY DEVICE AND MANUFACTURING METHOD THEREOF MAGNOLIA PURPLE CORPORATION (JP) 2008-03-27 US disclosed
US-20070026165-A1 Liquid crystal display and manufacturing method of same DAI NIPPON PRINTING CO., LTD. (JP) 2007-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100032620-A1 POLYMERIZABLE OPTICAL ACTIVE COMPOUND AND POLYMERIZABLE COMPOSITION CONTAINING THE SAME C1S, PYM1, MCCC2 THRB 3247/4885RARB 3096/4885RARA 2388/4885
US-20090050844-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION H1-0, H1-4, H1-10 THRB 3657/4885RARB 3123/4885RARA 2460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.