Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6899452 | 0.74 | ATM (0.48) | ALDH1A1MAPTATMMCL1CES2 | |
| SCHEMBL5011476 | 0.65 | — | — | |
| SCHEMBL1252912 | 0.63 | ATM (0.48) | ALDH1A1MAPTATMMCL1CES2 | |
| SCHEMBL14642602 | 0.62 | ALDH1A1 (0.63) | ALDH1A1MAPTATMMCL1CES2 | |
| SCHEMBL19074432 | 0.62 | ALDH1A1 (0.42) | ALDH1A1MAPTATMMCL1CES2 | |
| SCHEMBL5038883 | 0.60 | MAPT (0.50) | ALDH1A1MAPTATMMCL1CES2 | |
| SCHEMBL49783 | 0.59 | MAPT (0.50) | ALDH1A1MAPTATMMCL1CES2 | |
| SCHEMBL15058852 | 0.59 | MAPT (0.39) | ALDH1A1MAPTATMMCL1CES2 | |
| SCHEMBL14754529 | 0.58 | — | — | |
| SCHEMBL5829345 | 0.58 | ALDH1A1 (0.36) | ALDH1A1MAPTATMMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169356-A1 | POLYOLEFIN PRODUCTION | ATOFINA Research (BE) | 2002-01-09 | — | — | EP | disclosed |
| WO-2000049029-A1 | POLYOLEFIN PRODUCTION | FINA RESEARCH S.A. (BE) | 2000-08-24 | — | — | WO | disclosed |
| WO-2000049056-A1 | POLYOLEFIN PRODUCTION | ATOFINA RESEARCH (BE) | 2000-08-24 | — | — | WO | disclosed |