Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 5/20 | 0.34 |
| ▸ | KDM4D | Q6B0I6 | 5/20 | 0.33 |
| ▸ | DRD2 | P14416 | 4/20 | 0.33 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.31 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | KAT7 | O95251 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7554372 | 0.89 | KDM4D (0.38) | BTKKDM4DDRD2DRD3PARP1 | |
| SCHEMBL7516546 | 0.86 | BTK (0.39) | BTKKDM4D | |
| SCHEMBL7559538 | 0.86 | MELK (0.33) | BTKDRD2KAT7 | |
| SCHEMBL4515547 | 0.85 | KAT8 (0.38) | BTKKDM4DDRD2KAT8DRD3 | |
| SCHEMBL7512228 | 0.83 | KDM4D (0.33) | BTKKDM4DDRD2DRD3PARP1 | |
| SCHEMBL7581762 | 0.82 | AAK1 (0.36) | BTKKDM4DKAT8KAT6A | |
| SCHEMBL7514863 | 0.82 | IRAK1 (0.37) | DRD2KAT7 | |
| SCHEMBL4512030 | 0.81 | POLB (0.38) | KAT7 | |
| SCHEMBL7508482 | 0.80 | BTK (0.38) | BTKKDM4D | |
| SCHEMBL4713638 | 0.80 | BTK (0.39) | BTKKDM4DPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255739-A1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2002-11-13 | — | — | EP | disclosed |
| WO-2001053273-A1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2001-07-26 | — | — | WO | disclosed |