SCHEMBL751337

SCHEMBL751337

O=C(O)c1c(-c2ccccc2)ccc(S(=O)(=O)O)c1C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 2/20 0.41
TSHR P16473 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
FABP4 P15090 2/20 0.37
FABP5 Q01469 2/20 0.37
HNF4A P41235 1/20 0.37
KMT2A Q03164 3/20 0.36
MEN1 O00255 2/20 0.36
HSD17B10 Q99714 2/20 0.36
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
CYP1A2 P05177 1/20 0.36
GLA P06280 1/20 0.36
HPGD P15428 1/20 0.36
CYP2C19 P33261 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
MMP1 P03956 1/20 0.36
MMP2 P08253 1/20 0.36
MMP9 P14780 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL751984 0.83 CYP1A2 (0.45) TSHRKMT2AMEN1HSD17B10KDM4E
SCHEMBL23521242 0.82 FOLH1 (0.53) FOLH1TSHRFABP4FABP5HNF4A
SCHEMBL2548807 0.79 MEN1 (0.46) TSHRKMT2AMEN1HSD17B10KDM4E
SCHEMBL21879681 0.78 CDC25B (0.50) FOLH1TSHRSMN1; SMN2HNF4AKMT2A
SCHEMBL29093358 0.78 CYP2D6 (0.41) FOLH1TSHRSMN1; SMN2HNF4AKMT2A
SCHEMBL27498472 0.77 FOLH1 (0.38) FOLH1TSHRSMN1; SMN2FABP4FABP5
SCHEMBL28614880 0.76 TSHR (0.41) TSHRSMN1; SMN2FABP4FABP5HSD17B10
SCHEMBL15851422 0.76 TTR (0.48) TSHRSMN1; SMN2FABP4FABP5KMT2A
SCHEMBL29353151 0.75 PTGS2 (0.48) TSHRSMN1; SMN2HNF4AKMT2AMEN1
SCHEMBL140117 0.75 PTGS2 (0.48) TSHRSMN1; SMN2HNF4AKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110095109-A1 Process for Producing Polyester Pellets CLARIANT FINANCE (BVI) LIMITED (VG) 2011-04-28 US claimed
US-20130045912-A1 Colored Polyester CLARIANT FINANCE (BVI) LIMITED (VG) 2013-02-21 US disclosed
EP-2431456-A1 New amphiphile polycondensates and use of same in combination with polyester or surfaces containing polyester Polyprec GmbH (DE) 2012-03-21 EP disclosed
US-20110095109-A1 Process for Producing Polyester Pellets CLARIANT FINANCE (BVI) LIMITED (VG) 2011-04-28 US disclosed
EP-2291428-A1 PROCESS FOR PRODUCING POLYESTER PELLETS Clariant Finance (BVI) Limited (VG) 2011-03-09 EP disclosed
WO-2009152994-A1 PROCESS FOR PRODUCING POLYESTER PELLETS CLARIANT INTERNATIONAL LTD (CH) 2009-12-23 WO disclosed
US-5710117-A HYDRATED ZEOLITE, POLYALKYLENE TEREPHTHALATE-POLYOXYALKYLENEBISURETHANE COPOLYMER RHONE-POULENC CHIMIE (FR) 1998-01-20 US disclosed
EP-0066944-B1 ANIONIC TEXTILE TREATING COMPOSITION ICI AMERICAS INC. (US) 1986-11-20 EP disclosed
US-4427557-A POLYESTERETHER FROM ETHYLENE GLYCOL, POLYOXYETHYLENE GLYCOL, ARYLDICARBOXY ACID, AND SULFOARYLDICARBOXY/ ACID ICI AMERICAS INC. (US) 1984-01-24 US disclosed
EP-0066944-A1 Anionic textile treating composition ICI AMERICAS INC. (US) 1982-12-15 EP disclosed