Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.83 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.83 |
| ▸ | NPC1 | O15118 | 2/20 | 0.82 |
| ▸ | RAB9A | P51151 | 2/20 | 0.82 |
| ▸ | RORC | P51449 | 1/20 | 0.80 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.70 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.70 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.70 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.70 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | XBP1 | P17861 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.66 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.66 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.66 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2064051 | 0.93 | TRPV1 (0.73) | TRPV1PTGS1NPC1RAB9ARORC | |
| SCHEMBL2923145 | 0.93 | TRPV1 (0.73) | TRPV1PTGS1NPC1RAB9ARORC | |
| SCHEMBL674439 | 0.93 | HDAC6 (0.82) | TRPV1PTGS1NPC1RAB9ARORC | |
| SCHEMBL11730950 | 0.93 | NPC1 (0.77) | TRPV1PTGS1NPC1RAB9ARORC | |
| SCHEMBL15948139 | 0.91 | TRPV1 (0.76) | TRPV1PTGS1NPC1RAB9ARORC | |
| SCHEMBL96039 | 0.91 | TRPV1 (0.71) | TRPV1PTGS1NPC1RAB9ARORC | |
| SCHEMBL28910371 | 0.91 | TRPV1 (0.71) | TRPV1PTGS1NPC1RAB9ARORC | |
| SCHEMBL95224 | 0.91 | TRPV1 (0.71) | TRPV1PTGS1NPC1RAB9ARORC | |
| SCHEMBL22721382 | 0.91 | PTGS1 (0.76) | TRPV1PTGS1NPC1RAB9ARORC | |
| SCHEMBL7557294 | 0.91 | TRPV1 (1.00) | TRPV1PTGS1NPC1RAB9ARORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001021160-B1 | CARBOXYMIDE AND ANILINE DERIVATIVES AS SELECTIVE INHIBITORS OF PATHOGENS | AXXIMA PHARMACEUTICALS AG (DE) | 2002-05-30 | — | — | WO | claimed |