Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 6/20 | 1.00 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.71 |
| ▸ | NPC1 | O15118 | 2/20 | 0.70 |
| ▸ | RAB9A | P51151 | 2/20 | 0.70 |
| ▸ | RORC | P51449 | 1/20 | 0.69 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.59 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | XBP1 | P17861 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.57 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.57 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.57 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7513604 | 0.91 | TRPV1 (0.83) | TRPV1PTGS1NPC1RAB9ARORC | |
| SCHEMBL3674376 | 0.87 | TRPV1 (0.76) | TRPV1NPC1RAB9AMEN1LMNA | |
| SCHEMBL12334375 | 0.85 | RORC (0.77) | TRPV1PTGS1NPC1RAB9ARORC | |
| SCHEMBL11730950 | 0.84 | NPC1 (0.77) | TRPV1PTGS1NPC1RAB9ARORC | |
| SCHEMBL2923145 | 0.84 | TRPV1 (0.73) | TRPV1PTGS1NPC1RAB9ARORC | |
| SCHEMBL674439 | 0.84 | HDAC6 (0.82) | TRPV1PTGS1NPC1RAB9ARORC | |
| SCHEMBL2064051 | 0.84 | TRPV1 (0.73) | TRPV1PTGS1NPC1RAB9ARORC | |
| SCHEMBL12334058 | 0.83 | TRPV1 (0.70) | TRPV1PTGS1NPC1RAB9ARORC | |
| SCHEMBL22721382 | 0.83 | PTGS1 (0.76) | TRPV1PTGS1NPC1RAB9ARORC | |
| SCHEMBL96039 | 0.83 | TRPV1 (0.71) | TRPV1PTGS1NPC1RAB9ARORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001021160-B1 | CARBOXYMIDE AND ANILINE DERIVATIVES AS SELECTIVE INHIBITORS OF PATHOGENS | AXXIMA PHARMACEUTICALS AG (DE) | 2002-05-30 | — | — | WO | claimed |
| CN-109311914-B | Lanthanide tool box for organelle specific molecular imaging | 新生命医药科技有限公司 | 2021-07-13 | — | — | CN | disclosed |
| EP-3464299-B1 | LANTHANIDE TOOLBOX FOR ORGANELLE SPECIFIC MOLECULAR IMAGING | NEW LIFE MEDICINE TECH COMPANY LIMITED (CN) | 2021-01-13 | — | — | EP | disclosed |
| US-10787465-B2 | Lanthanide toolbox for organelle specific molecular imaging with multi-color | NEW LIFE MEDICINE TECHNOLOGY COMPANY LIMITED (CN) | 2020-09-29 | — | — | US | disclosed |
| US-20190127393-A1 | Lanthanide Toolbox for Organelle Specific Molecular Imaging with Multi-color | NEW LIFE MEDICINE TECHNOLOGY COMPANY LIMITED (HK) | 2019-05-02 | — | — | US | disclosed |
| CN-109311914-A | Lanthanide tool box for organelle specific molecular imaging | 新生命医药科技有限公司 | 2019-02-05 | — | — | CN | disclosed |
| US-10183956-B2 | Lanthanide toolbox for organelle specific molecular imaging | NEW LIFE MEDICINE TECHNOLOGY COMPANY LIMITED (HK) | 2019-01-22 | — | — | US | disclosed |
| US-20170342090-A1 | Lanthanide Toolbox for Organelle Specific Molecular Imaging | NEW LIFE MEDICINE TECHNOLOGY COMPANY LIMITED (HK) | 2017-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10183956-B2 | Lanthanide toolbox for organelle specific molecular imaging | COG5, NLN, KIF5A | TRPV1 2260/4885PTGS1 4447/4885NPC1 593/4885 |
| US-20170342090-A1 | Lanthanide Toolbox for Organelle Specific Molecular Imaging | COG5, NLN, KIF5A | TRPV1 2260/4885PTGS1 4447/4885NPC1 593/4885 |
| US-20190127393-A1 | Lanthanide Toolbox for Organelle Specific Molecular Imaging with Multi-color | DYNC1LI2, DYNLL2, DYNLL1 | TRPV1 2473/4885PTGS1 4789/4885NPC1 420/4885 |
| US-10787465-B2 | Lanthanide toolbox for organelle specific molecular imaging with multi-color | DYNC1LI2, DYNLL2, DYNLL1 | TRPV1 2473/4885PTGS1 4789/4885NPC1 420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.