SCHEMBL7513608

SCHEMBL7513608

COc1ccc(C=Cc2ncnc(C(Cl)(Cl)Cl)n2)cc1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 5/20 0.41
KMT2A Q03164 3/20 0.37
EPHB4 P54760 1/20 0.37
MAPT P10636 2/20 0.37
ALDH1A1 P00352 1/20 0.37
HPGD P15428 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
GLA P06280 1/20 0.36
MEN1 O00255 2/20 0.36
NQO2 P16083 1/20 0.36
TUBB4A P04350 2/20 0.36
TUBB P07437 2/20 0.36
TUBA3C P0DPH7 2/20 0.36
TUBA1B P68363 2/20 0.36
TUBA4A P68366 2/20 0.36
TUBB4B P68371 2/20 0.36
TUBB3 Q13509 2/20 0.36
TUBB2A Q13885 2/20 0.36
TUBB8 Q3ZCM7 2/20 0.36
TUBA3E Q6PEY2 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21253271 0.90 MAPT (0.48) APPKMT2AMAPTALDH1A1HPGD
SCHEMBL1507965 0.87 TUBB1 (0.42) APPKMT2AMAPTALDH1A1HPGD
SCHEMBL14407712 0.87 TUBB1 (0.42) APPKMT2AMAPTALDH1A1HPGD
SCHEMBL3631929 0.80 MAPT (0.46) KMT2AMAPTALDH1A1HPGDSMN1; SMN2
SCHEMBL2176634 0.80 MAPT (0.46) KMT2AMAPTALDH1A1HPGDSMN1; SMN2
SCHEMBL5185776 0.78 CYP1A1 (0.49) KMT2AMAPTMEN1NQO2TUBB4A
SCHEMBL21940413 0.76 MAPT (0.53) APPKMT2AMAPTALDH1A1HPGD
SCHEMBL151090 0.76 MAPT (0.53) APPKMT2AMAPTALDH1A1HPGD
SCHEMBL29417481 0.76 MAPT (0.53) APPKMT2AMAPTALDH1A1HPGD
SCHEMBL151091 0.76 MAPT (0.53) APPKMT2AMAPTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020093284-A1 Light-emitting devices and light-emitting displays HITACHI, LTD. (JP) 2002-07-18 US disclosed