Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 10/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7511583 | 0.91 | GAA (0.38) | GAAPARP3PTGER1MCHR1 | |
| SCHEMBL7515830 | 0.89 | GAA (0.36) | GAAPTGER1CETP | |
| SCHEMBL7506976 | 0.88 | PTGER1 (0.37) | GAAPTGER1ABHD6CETP | |
| SCHEMBL7209116 | 0.86 | GAA (0.38) | GAAPTGER1ABHD6CETP | |
| SCHEMBL7516134 | 0.86 | PTGER1 (0.35) | GAAPTGER1PPARG | |
| Hydrochloric Acid SCHEMBL7144634 | 0.86 | PTGER1 (0.37) | PTGER1PPARGPPARDPPARAMCHR1 | |
| SCHEMBL8058096 | 0.84 | CETP (0.38) | GAAPTGER1ABHD6CETP | |
| Hydrochloric Acid SCHEMBL7146578 | 0.83 | PTGER1 (0.37) | PTGER1MCHR1ABHD6 | |
| SCHEMBL7516138 | 0.83 | PTGER1 (0.36) | GAAPTGER1CETP | |
| SCHEMBL7982398 | 0.83 | UTS2R (0.35) | GAAPTGER1CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051173-A4 | DERIVATIVES OF 1,3,4-OXADIAZOLONE | BRISTOL MYERS SQUIBB CO (US) | 2002-07-31 | — | — | EP | claimed |
| EP-1051173-A1 | DERIVATIVES OF 1,3,4-OXADIAZOLONE | Bristol-Myers Squibb Company (US) | 2000-11-15 | — | — | EP | claimed |
| US-6034113-A | ANTIISCHEMIC AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-03-07 | — | — | US | claimed |
| WO-1999038510-A1 | DERIVATIVES OF 1,3,4-OXADIAZOLONE | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-08-05 | — | — | WO | claimed |