Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 18/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 7/20 | 0.47 |
| ▸ | PTPRC | P08575 | 3/20 | 0.47 |
| ▸ | PTPRA | P18433 | 2/20 | 0.39 |
| ▸ | PTPRB | P23467 | 2/20 | 0.39 |
| ▸ | PTPRE | P23469 | 2/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.39 |
| ▸ | AIP | O00170 | 1/20 | 0.32 |
| ▸ | SGTA | O43765 | 1/20 | 0.32 |
| ▸ | TOMM70 | O94826 | 1/20 | 0.32 |
| ▸ | STIP1 | P31948 | 1/20 | 0.32 |
| ▸ | PPP5C | P53041 | 1/20 | 0.32 |
| ▸ | DNAJC7 | Q99615 | 1/20 | 0.32 |
| ▸ | STUB1 | Q9UNE7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5770421 | 0.78 | PTPN1 (0.52) | PTPN1PTPN2PTPRCPTPRAPTPRB | |
| SCHEMBL7518656 | 0.78 | PTPN1 (0.51) | PTPN1PTPN2PTPRCPTPRAPTPRB | |
| SCHEMBL7519532 | 0.76 | PTPN1 (0.47) | PTPN1PTPN2PTPRCPTPRAPTPRB | |
| SCHEMBL7515936 | 0.73 | PTPN1 (0.43) | PTPN1PTPN2PTPRCPTPRAPTPRB | |
| SCHEMBL7513085 | 0.73 | PTPN1 (0.47) | PTPN1PTPN2PTPRCPTPRAPTPRB | |
| SCHEMBL7521094 | 0.73 | PTPN1 (0.45) | PTPN1PTPN2PTPRCPTPRAPTPRB | |
| SCHEMBL7517024 | 0.72 | RAB9A (0.44) | PTPN1PTPN2PTPRCPTPRAPTPRB | |
| SCHEMBL7519819 | 0.72 | RAB9A (0.44) | PTPN1PTPN2PTPRCPTPRAPTPRB | |
| SCHEMBL7520464 | 0.72 | PTPN1 (0.44) | PTPN1PTPN2PTPRCPTPRAPTPRB | |
| SCHEMBL7520917 | 0.72 | PTPN1 (0.42) | PTPN1PTPN2PTPRCPTPRBPTPRE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020099073-A1 | Modulators of protein tyrosine phosphatases (PTPases) | NOVO NORDISK A/S (DK) | 2002-07-25 | — | — | US | claimed |
| WO-2002004458-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPASES) | NOVO NORDISK A/S (DK) | 2002-01-17 | — | — | WO | claimed |
| US-20020099073-A1 | Modulators of protein tyrosine phosphatases (PTPases) | NOVO NORDISK A/S (DK) | 2002-07-25 | — | — | US | disclosed |
| WO-2002004458-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPASES) | NOVO NORDISK A/S (DK) | 2002-01-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099073-A1 | Modulators of protein tyrosine phosphatases (PTPases) | PTPN1, PTPRO, PTPRS | PTPN1 1/4885PTPN2 14/4885PTPRC 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.