Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7503297 | 0.85 | PTGER1 (0.48) | PTGER1HPGDSMN1; SMN2TLR7PTGER4 | |
| SCHEMBL7498276 | 0.82 | TLR7 (0.54) | PTGER1TLR7 | |
| SCHEMBL7607568 | 0.81 | PTGER1 (0.53) | PTGER1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7509735 | 0.81 | PTGER1 (0.46) | PTGER1HPGDTLR7PTGER4PTGER3 | |
| SCHEMBL7502192 | 0.80 | PTGER1 (0.49) | PTGER1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7506287 | 0.80 | PTGER1 (0.46) | PTGER1HPGDTLR7PTGER4PTGER3 | |
| SCHEMBL7447138 | 0.80 | PTGER1 (0.54) | PTGER1TLR7 | |
| SCHEMBL7513283 | 0.80 | SMN1; SMN2 (0.50) | PTGER1SMN1; SMN2TLR7PTGER4PTGER3 | |
| SCHEMBL7448167 | 0.80 | PTGER1 (0.50) | PTGER1SMN1; SMN2TLR7 | |
| SCHEMBL7087561 | 0.80 | PTGER1 (0.52) | PTGER1KDM4EALDH1A1HPGDTLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977743-A1 | PROTEASE INHIBITORS | Smithkline Beecham (US) | 2000-02-09 | — | — | EP | claimed |
| WO-1998049152-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-11-05 | — | — | WO | claimed |