SCHEMBL7514337

SCHEMBL7514337

OC(O)n1cnc2ccccc21

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.58
MEN1 O00255 1/20 0.58
HPGD P15428 1/20 0.58
KMT2A Q03164 1/20 0.58
LMNA P02545 1/20 0.49
STAT6 P42226 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
TDP1 Q9NUW8 1/20 0.48
HDAC8 Q9BY41 1/20 0.48
HTT P42858 1/20 0.47
FGFR1 P11362 2/20 0.46
AGER Q15109 4/20 0.44
GGPS1 O95749 1/20 0.44
FDPS P14324 1/20 0.44
POLB P06746 2/20 0.43
MAPT P10636 1/20 0.43
TSHR P16473 1/20 0.43
MAPK1 P28482 1/20 0.43
TNF P01375 1/20 0.43
CYP11B1 P15538 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6094420 0.88 HSD17B10 (0.58) HSD17B10MEN1HPGDKMT2ALMNA
SCHEMBL9754107 0.84 HSD17B10 (0.54) HSD17B10MEN1HPGDKMT2ALMNA
SCHEMBL250816 0.84 MEN1 (0.64) HSD17B10MEN1HPGDKMT2ALMNA
SCHEMBL16504441 0.82 HSD17B10 (0.57) HSD17B10MEN1HPGDKMT2ALMNA
SCHEMBL8615932 0.81 HSD17B10 (0.65) HSD17B10MEN1HPGDKMT2ALMNA
SCHEMBL6284930 0.81 MEN1 (0.60) HSD17B10MEN1HPGDKMT2ALMNA
SCHEMBL4070928 0.81 MEN1 (0.60) HSD17B10MEN1HPGDKMT2ALMNA
SCHEMBL6174314 0.81 MEN1 (0.60) HSD17B10MEN1HPGDKMT2ALMNA
SCHEMBL5884242 0.80 HSD17B10 (0.50) HSD17B10MEN1HPGDKMT2ALMNA
SCHEMBL17329321 0.80 HSD17B10 (0.50) HSD17B10MEN1HPGDKMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1227785-A2 PROCESS FOR PRODUCING A HAIRDYE COMPOSITION Lion Corporation (JP) 2002-08-07 EP disclosed
EP-1189576-A2 HAIR COMPOSITION COMPRISING AN OXIDASE AND CYCLODEXTRIN Lion Corporation (JP) 2002-03-27 EP disclosed
EP-1187596-A2 HAIRDYE COMPOSITION COMPRISING INDOLINE AND/OR AN INDOLINE COMPOUND AND LACCASE Lion Corporation (JP) 2002-03-20 EP disclosed
EP-1165027-A1 HAIRDYE COMPOSITION OF SINGLE PREPARATION TYPE CONTAINING AN OXIDASE Lion Corporation (JP) 2002-01-02 EP disclosed
WO-2001068042-A1 METHOD FOR DYEING DRY HAIR NOVOZYMES A/S (DK) 2001-09-20 WO disclosed
WO-2001000144-A2 HAIR COMPOSITION COMPRISING AN OXIDASE AND CYCLODEXTRIN LION CORPORATION (JP) 2001-01-04 WO disclosed
WO-2000078274-A2 HAIRDYE COMPOSITION COMPRISING INDOLINE AND/OR AN INDOLINE COMPOUND AND LACCASE LION CORPORATION (JP) 2000-12-28 WO disclosed
WO-2000078273-A2 PROCESS FOR PRODUCING A HAIRDYE COMPOSITION LION CORPORATION (JP) 2000-12-28 WO disclosed
WO-2000059459-A1 HAIRDYE COMPOSITION OF SINGLE PREPARATION TYPE CONTAINING AN OXIDASE LION CORPORATION (JP) 2000-10-12 WO disclosed