SCHEMBL751448

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL751449	1.00	MEN1 (0.43)	MEN1KMT2AMAPTCYP1A2CYP2C19
	SCHEMBL754615	0.89	MEN1 (0.44)	MEN1KMT2AMAPTCYP1A2CYP2C19
	SCHEMBL754614	0.89	MEN1 (0.44)	MEN1KMT2AMAPTCYP1A2CYP2C19
	SCHEMBL765088	0.84	NPC1 (0.46)	MEN1KMT2AMAPTCYP1A2CYP2C19
	SCHEMBL753939	0.84	NPC1 (0.46)	MEN1KMT2AMAPTCYP1A2CYP2C19
	SCHEMBL753019	0.81	MAPT (0.47)	MEN1KMT2AMAPTCYP1A2CYP2C19
	SCHEMBL16921582	0.81	MAPT (0.47)	MEN1KMT2AMAPTCYP1A2CYP2C19
	SCHEMBL752479	0.81	MEN1 (0.44)	MEN1KMT2AMAPTCYP1A2CYP2C19
	SCHEMBL752478	0.81	MEN1 (0.44)	MEN1KMT2AMAPTCYP1A2CYP2C19
	SCHEMBL755353	0.78	MEN1 (0.47)	MEN1KMT2AMAPTCYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.