Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 11/20 | 0.41 |
| ▸ | ACACA | Q13085 | 10/20 | 0.41 |
| ▸ | SUV39H2 | Q9H5I1 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | CKS1B | P61024 | 1/20 | 0.37 |
| ▸ | SKP1 | P63208 | 1/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7514863 | 0.89 | IRAK1 (0.37) | ACACBACACASUV39H2DRD2PRMT5 | |
| SCHEMBL4506830 | 0.86 | ACACB (0.41) | ACACBACACASUV39H2DRD2CKS1B | |
| SCHEMBL7517651 | 0.84 | ACACB (0.39) | ACACBACACASUV39H2DRD2CKS1B | |
| SCHEMBL7515377 | 0.82 | DRD2 (0.30) | DRD2 | |
| SCHEMBL4525305 | 0.82 | PRMT5 (0.39) | ACACBACACASUV39H2DRD2PRMT5 | |
| SCHEMBL4501738 | 0.82 | ACACB (0.43) | ACACBACACASUV39H2DRD2CKS1B | |
| SCHEMBL7554372 | 0.81 | KDM4D (0.38) | SUV39H2DRD2 | |
| SCHEMBL4512791 | 0.80 | KCNH2 (0.43) | ACACBACACASUV39H2CKS1BSKP1 | |
| SCHEMBL4506561 | 0.78 | ACACB (0.40) | ACACBACACASUV39H2DRD2CKS1B | |
| SCHEMBL4500327 | 0.78 | ACACB (0.42) | ACACBACACASUV39H2DRD2CKS1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255739-A1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2002-11-13 | — | — | EP | disclosed |
| WO-2001053273-A1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2001-07-26 | — | — | WO | disclosed |