Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7514650 | 1.00 | CDK2 (0.34) | CDK2 | |
| SCHEMBL7523057 | 0.87 | HTT (0.37) | — | |
| SCHEMBL7523062 | 0.87 | HTT (0.37) | — | |
| SCHEMBL7775773 | 0.85 | — | — | |
| SCHEMBL7775770 | 0.85 | — | — | |
| SCHEMBL1388949 | 0.82 | CDK2 (0.32) | CDK2 | |
| SCHEMBL7514661 | 0.82 | CDK2 (0.32) | CDK2 | |
| SCHEMBL7575702 | 0.82 | SIRT2 (0.33) | CDK2 | |
| SCHEMBL1388950 | 0.82 | CDK2 (0.32) | CDK2 | |
| SCHEMBL1389051 | 0.82 | CDK2 (0.32) | CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0866701-B1 | SYNERGISTIC IMMUNOSUPPRESSANT COMPOSITION CONTAINING A 2,2'-BI-1H-PYRROLE COMPOUND | PHARMACIA & UPJOHN SPA (IT) | 2002-01-16 | — | — | EP | claimed |
| EP-0825983-B1 | PROCESS FOR THE PREPARATION OF 2,2'-BIPYRROLYL-PYRROMETHENE (PRODIGIOSINS) DERIVATIVES | PHARMACIA & UPJOHN SPA (IT) | 2001-08-29 | — | — | EP | claimed |
| EP-0975338-A2 | 2,2'-BI-1H-PYRROLE DERIVATIVES USEFUL IN THE TREATMENT OF LEUKEMIA BROUGHT ON BY HTLV-I | PHARMACIA & UPJOHN S.p.A. (IT) | 2000-02-02 | — | — | EP | claimed |
| WO-1999029309-A2 | 2,2'-BI-1H-PYRROLE DERIVATIVES USEFUL IN THE TREATMENT OF LEUKEMIA BROUGHT ON BY HTLV-I | PHARMACIA & UPJOHN S.P.A. (IT) | 1999-06-17 | — | — | WO | claimed |
| EP-0866701-B1 | SYNERGISTIC IMMUNOSUPPRESSANT COMPOSITION CONTAINING A 2,2'-BI-1H-PYRROLE COMPOUND | PHARMACIA & UPJOHN SPA (IT) | 2002-01-16 | — | — | EP | disclosed |
| US-6291509-B1 | Synergistic immunosuppressant composition containing a 2,2'-bi-1H-pyrrole compound | PHARMACIA & UPJOHN SPA (IT) | 2001-09-18 | — | — | US | disclosed |
| EP-0866701-A1 | SYNERGISTIC IMMUNOSUPPRESSANT COMPOSITION CONTAINING A 2,2'-BI-1H-PYRROLE COMPOUND | PHARMACIA & UPJOHN S.p.A. (IT) | 1998-09-30 | — | — | EP | disclosed |
| WO-1998011894-A1 | SYNERGISTIC IMMUNOSUPPRESSANT COMPOSITION CONTAINING A 2,2'-BI-1H-PYRROLE COMPOUND | PHARMACIA & UPJOHN S.P.A. (IT) | 1998-03-26 | — | — | WO | disclosed |