SCHEMBL7514905

SCHEMBL7514905

CCCCCCCCCCCCCCCCCCOC(=O)c1ccc(Cl)cc1Cl

nearest known ligand 0.70

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.70
TSHR P16473 3/20 0.60
ALDH1A1 P00352 3/20 0.60
LMNA P02545 1/20 0.60
TP53 P04637 1/20 0.58
CYP3A4 P08684 1/20 0.58
MAPK1 P28482 1/20 0.58
POLB P06746 2/20 0.54
KDM4E B2RXH2 1/20 0.54
HSD17B10 Q99714 1/20 0.54
TDP1 Q9NUW8 3/20 0.52
L3MBTL1 Q9Y468 3/20 0.52
THRB P10828 1/20 0.49
RECQL P46063 1/20 0.49
ESR1 P03372 1/20 0.49
NPC1 O15118 1/20 0.49
MAPT P10636 1/20 0.49
RAB9A P51151 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9706036 1.00 KMT2A (0.70) KMT2ATSHRALDH1A1LMNATP53
SCHEMBL7512739 1.00 KMT2A (0.70) KMT2ATSHRALDH1A1LMNATP53
SCHEMBL18481835 0.94 KMT2A (0.73) KMT2ATSHRALDH1A1LMNATP53
SCHEMBL7521488 0.92 KMT2A (0.61) KMT2ATSHRALDH1A1LMNATP53
SCHEMBL7521475 0.92 KMT2A (0.61) KMT2ATSHRALDH1A1LMNATP53
SCHEMBL4628079 0.90 TSHR (0.67) KMT2ATSHRALDH1A1LMNATP53
SCHEMBL21113682 0.90 TSHR (0.67) KMT2ATSHRALDH1A1LMNATP53
SCHEMBL7520602 0.88 KMT2A (0.68) KMT2ATSHRALDH1A1CYP3A4MAPK1
SCHEMBL27768733 0.86 TSHR (0.61) KMT2ATSHRALDH1A1LMNATP53
SCHEMBL5709895 0.86 TSHR (0.57) KMT2ATSHRALDH1A1LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020028413-A1 Method of dispersing water insoluble photographically useful compounds EASTMAN KODAK COMPANY 2002-03-07 US disclosed
EP-0555923-B1 Photographic additive dispersions and a method of preparing the same EASTMAN KODAK CO (US) 1998-11-18 EP disclosed
US-5688959-A MULTICOLOR DYE IMAGE AND INFRARED RADIATION ABSORBER WITH 1-HYDROXY-2-N-(5-ALKYLTHIAZOL-2-YL)NAPHTHAMIDE COUPLERS FORMING QUINONE IMINE DYES AGFA-GEVAERT, N.V. (BE) 1997-11-18 US disclosed
US-5310632-A Photographic additive dispersions and a method of preparing the same EASTMAN KODAK COMPANY (US) 1994-05-10 US disclosed
EP-0555923-A2 Photographic additive dispersions and a method of preparing the same EASTMAN KODAK COMPANY (US) 1993-08-18 EP disclosed
US-5030544-A 1-hydroxy-2-n(5-alkyl thiazol 2-yl) naphthamides, form quinone-imine dyes AGFA-GEVAERT, N.V. (BE) 1991-07-09 US disclosed
US-4977052-A Electro-statographic toner material FUJI PHOTO FILM CO., LTD. (JP) 1990-12-11 US disclosed
US-4933249-A Electrostatographic pressure fixing process using encapsulated toner particles FUJI PHOTO FILM CO., LTD. (JP) 1990-06-12 US disclosed
US-4803144-A Electrophotographic encapsulated pressure fixable toner particles with electroconductive powder coating FUJI PHOTO FILM CO., LTD. (JP) 1989-02-07 US disclosed
EP-0176628-B1 PHOTOGRAPHIC COLOUR ELEMENTS AGFA-GEVAERT N.V. (BE) 1987-11-25 EP disclosed
US-4442194-A Preparation of encapsulated electrostatographic toner material using gelatin derivative FUJI PHOTO FILM CO., LTD. (JP) 1984-04-10 US disclosed
US-4430421-A USING IHYDROXYMETHYL(5,2,1,0(2,6))TRICYCLODECANE, OR CARBOXYLIC, PHOSPHORIC, OR PHOSPHONIC DIESTERS THEREOF AGFA-GEVAERT, N.V. (BE) 1984-02-07 US disclosed
US-4430422-A USING 1,3-DIALKYLOXY-2-PROPANOLS AND CARBOXYLIC, PHOSPHORIC OR PHOSPHONIC ESTERS THEREOF AGFA-GEVAERT, N.V. (BE) 1984-02-07 US disclosed
EP-0084694-A1 Method of dispersing photographic adjuvants in hydrophilic colloid compositions AGFA-GEVAERT N.V. (BE) 1983-08-03 EP disclosed
EP-0084692-A2 Method of dispersing photographic adjuvants in a hydrophilic colloid composition AGFA-GEVAERT N.V. (BE) 1983-08-03 EP disclosed
US-4291113-A IN WATER OR HYDROPHILIC COLLOID BY USE OF POLYMER OF UNSATURATED SULFONATE FUJI PHOTO FILM CO., LTD. (JP) 1981-09-22 US disclosed
US-4275145-A ANIONIC SURFACTANT, LECITHIN AND GELATIN DERIVATIVE FUJI PHOTO FILM CO., LTD. (JP) 1981-06-23 US disclosed
US-4239851-A DISSOLVING AN OIL SOLUBLE ADDITIVE IN AN EPOXY COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1980-12-16 US disclosed
US-4211836-A LECITHIN AND AN ANIONIC SURFACTANT CONTAINING A SULFATE OR SULFONATE GROUP FUJI PHOTO FILM CO., LTD. (JP) 1980-07-08 US disclosed
US-4181527-A HYDROPHILIC COLLOID FUJI PHOTO FILM CO., LTD. (JP) 1980-01-01 US disclosed