SCHEMBL7520602

SCHEMBL7520602

CCCOC(=O)c1ccc(Cl)cc1Cl

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.68
ALDH1A1 P00352 3/20 0.56
POLB P06746 1/20 0.54
THRB P10828 1/20 0.54
RECQL P46063 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
CHRM2 P08172 1/20 0.52
CHRM3 P20309 1/20 0.52
MAOA P21397 1/20 0.52
HTR2C P28335 1/20 0.52
CHRNA4 P43681 1/20 0.52
HTR3A P46098 1/20 0.52
KCNH2 Q12809 1/20 0.52
HRH3 Q9Y5N1 1/20 0.52
MAPT P10636 2/20 0.50
TSHR P16473 1/20 0.50
CASP1 P29466 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
MAPK1 P28482 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18481835 0.90 KMT2A (0.73) KMT2AALDH1A1POLBTHRBRECQL
SCHEMBL15675574 0.88 ALDH1A1 (0.62) KMT2AALDH1A1POLBTHRBRECQL
SCHEMBL7514905 0.88 KMT2A (0.70) KMT2AALDH1A1POLBTHRBRECQL
SCHEMBL9706036 0.88 KMT2A (0.70) KMT2AALDH1A1POLBTHRBRECQL
SCHEMBL7512739 0.88 KMT2A (0.70) KMT2AALDH1A1POLBTHRBRECQL
SCHEMBL522136 0.86 KMT2A (0.59) KMT2AALDH1A1POLBTHRBRECQL
SCHEMBL10487722 0.85 ALDH1A1 (0.54) KMT2AALDH1A1POLBTDP1L3MBTL1
SCHEMBL10487737 0.85 ALDH1A1 (0.54) KMT2AALDH1A1POLBTHRBRECQL
SCHEMBL20267301 0.84 ALDH1A1 (0.53) KMT2AALDH1A1TDP1L3MBTL1CHRM2
SCHEMBL10487763 0.83 ALDH1A1 (0.51) KMT2AALDH1A1POLBTHRBRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020028413-A1 Method of dispersing water insoluble photographically useful compounds EASTMAN KODAK COMPANY 2002-03-07 US disclosed
US-5688959-A MULTICOLOR DYE IMAGE AND INFRARED RADIATION ABSORBER WITH 1-HYDROXY-2-N-(5-ALKYLTHIAZOL-2-YL)NAPHTHAMIDE COUPLERS FORMING QUINONE IMINE DYES AGFA-GEVAERT, N.V. (BE) 1997-11-18 US disclosed
EP-0478390-B1 Improved method for the preparation of 4-methylsulfonyl benzoic acid derivatives and intermediates ZENECA LTD (GB) 1995-02-22 EP disclosed
EP-0373573-B1 Recording material for ink jet printing CIBA GEIGY AG (CH) 1994-06-22 EP disclosed
US-5310632-A Photographic additive dispersions and a method of preparing the same EASTMAN KODAK COMPANY (US) 1994-05-10 US disclosed
EP-0555923-A2 Photographic additive dispersions and a method of preparing the same EASTMAN KODAK COMPANY (US) 1993-08-18 EP disclosed
EP-0359710-B1 OPTICAL BRIGHTENING AGENTS CIBA-GEIGY AG (CH) 1993-06-16 EP disclosed
EP-0280650-B1 USE OF PREDETERMINED BENZTRIAZOLE DERIVATIVES AS LIGHT-PROTECTING AGENTS FOR INK JET RECORDING MATERIALS CIBA-GEIGY AG (CH) 1992-04-08 EP disclosed
EP-0478390-A1 Improved method for the preparation of 4-methylsulfonyl benzoic acid derivatives and intermediates ZENECA LIMITED (GB) 1992-04-01 EP disclosed
US-5079381-A Method for the preparation of 4-methylsulfonyl benzoic acid derivatives and intermediates IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-01-07 US disclosed
US-4291113-A IN WATER OR HYDROPHILIC COLLOID BY USE OF POLYMER OF UNSATURATED SULFONATE FUJI PHOTO FILM CO., LTD. (JP) 1981-09-22 US disclosed
US-4275145-A ANIONIC SURFACTANT, LECITHIN AND GELATIN DERIVATIVE FUJI PHOTO FILM CO., LTD. (JP) 1981-06-23 US disclosed
US-4264722-A A COLORLESS CYAN-COLOR-FORMING COUPLER COMPRISING 4-OXY-DERIVATIVES OF 1-HYDROXY-2-SEC-AMIDO-NAPHTHALENE OR BENZENE FUJI PHOTO FILM CO., LTD. (JP) 1981-04-28 US disclosed
US-4254212-A ALKOXY SUBSTITUTED SULFONYL FUJI PHOTO FILM CO., LTD. (JP) 1981-03-03 US disclosed
EP-0024033-A1 Photographic colour couplers and light-sensitive material containing them FUJI PHOTO FILM CO., LTD. (JP) 1981-02-18 EP disclosed
US-4239851-A DISSOLVING AN OIL SOLUBLE ADDITIVE IN AN EPOXY COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1980-12-16 US disclosed
US-4228233-A CYAN DYE FORMING, COLORLESS COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1980-10-14 US disclosed
US-4211836-A LECITHIN AND AN ANIONIC SURFACTANT CONTAINING A SULFATE OR SULFONATE GROUP FUJI PHOTO FILM CO., LTD. (JP) 1980-07-08 US disclosed
US-4181527-A HYDROPHILIC COLLOID FUJI PHOTO FILM CO., LTD. (JP) 1980-01-01 US disclosed
US-3966728-A ANTIPEPTIC ULCER ACTIVITY NIPPON SHINYAKU CO., LTD. (JA) 1976-06-29 US disclosed