Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.82 |
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | MMP2 | P08253 | 3/20 | 0.51 |
| ▸ | MMP9 | P14780 | 3/20 | 0.51 |
| ▸ | MMP8 | P22894 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | CASP3 | P42574 | 2/20 | 0.51 |
| ▸ | MMP13 | P45452 | 2/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | NOS1 | P29475 | 1/20 | 0.49 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.49 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14904717 | 0.91 | CYP19A1 (0.69) | CYP19A1NPC1POLBMEN1KMT2A | |
| SCHEMBL14694251 | 0.91 | CYP19A1 (0.74) | CYP19A1NPC1POLBMEN1KMT2A | |
| SCHEMBL18180609 | 0.91 | CYP19A1 (0.74) | CYP19A1NPC1POLBMEN1KMT2A | |
| SCHEMBL19739173 | 0.91 | CYP19A1 (0.74) | CYP19A1NPC1POLBMEN1KMT2A | |
| SCHEMBL18160165 | 0.91 | CYP19A1 (0.74) | CYP19A1NPC1POLBMEN1KMT2A | |
| SCHEMBL30054382 | 0.90 | CYP19A1 (1.00) | CYP19A1NPC1POLBMEN1KMT2A | |
| SCHEMBL1465536 | 0.90 | CYP19A1 (1.00) | CYP19A1NPC1POLBMEN1KMT2A | |
| SCHEMBL1673078 | 0.90 | CYP19A1 (0.76) | CYP19A1NPC1POLBMEN1KMT2A | |
| SCHEMBL4866651 | 0.88 | CYP19A1 (0.65) | CYP19A1NPC1POLBMEN1KMT2A | |
| SCHEMBL10172987 | 0.88 | CYP19A1 (0.65) | CYP19A1NPC1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165512-A2 | METHOD FOR ARYLATING AZA-HETEROCYCLES WITH ACTIVATED AROMATIC COMPOUNDS IN THE PRESENCE OF CESIUM CARBONATE | GÖDECKE GMBH (DE) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000059883-A2 | METHOD FOR PRODUCING N-ARYL-AZA-HETEROCYCLES IN THE PRESENCE OF CESIUM CARBONATE | Gödecke GmbH (DE) | 2000-10-12 | — | — | WO | disclosed |