Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.76 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.55 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.55 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.55 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | NOS1 | P29475 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10172981 | 0.90 | CYP19A1 (0.64) | CYP19A1POLBNPC1MEN1KMT2A | |
| SCHEMBL7514925 | 0.90 | CYP19A1 (0.82) | CYP19A1POLBNPC1MEN1KMT2A | |
| SCHEMBL30054382 | 0.87 | CYP19A1 (1.00) | CYP19A1POLBNPC1MEN1KMT2A | |
| SCHEMBL1465536 | 0.87 | CYP19A1 (1.00) | CYP19A1POLBNPC1MEN1KMT2A | |
| SCHEMBL13062870 | 0.87 | CYP19A1 (0.64) | CYP19A1POLBNPC1MEN1KMT2A | |
| SCHEMBL7912335 | 0.84 | CYP19A1 (0.69) | CYP19A1POLBNPC1MEN1KMT2A | |
| SCHEMBL14694251 | 0.84 | CYP19A1 (0.74) | CYP19A1POLBNPC1MEN1KMT2A | |
| SCHEMBL7133332 | 0.84 | CYP19A1 (0.74) | CYP19A1POLBNPC1MEN1KMT2A | |
| SCHEMBL18160165 | 0.84 | CYP19A1 (0.74) | CYP19A1POLBNPC1MEN1KMT2A | |
| SCHEMBL18180609 | 0.84 | CYP19A1 (0.74) | CYP19A1POLBNPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110097707-A1 | RNAi Agents Comprising Universal Nucleobases | ALNYLAM PHARMACEUTICALS, INC. (US) | 2011-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110097707-A1 | RNAi Agents Comprising Universal Nucleobases | NOP2, NOP58, FBL | CYP19A1 4313/4885POLB 1180/4885NPC1 2546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.