Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.42 |
| ▸ | ARG2 | P78540 | 3/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | ARG1 | P05089 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GGT1 | P19440 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3803860 | 0.83 | FAAH (0.43) | GPR84FFAR1FFAR4ALDH1A1MEN1 | |
| SCHEMBL5473167 | 0.81 | FAAH (0.52) | GPR84FFAR1FFAR4ALDH1A1MEN1 | |
| SCHEMBL27809919 | 0.79 | FAAH (0.53) | GPR84FFAR1FFAR4ALDH1A1MEN1 | |
| SCHEMBL27606031 | 0.79 | FAAH (0.53) | GPR84FFAR1FFAR4ALDH1A1MEN1 | |
| SCHEMBL27455275 | 0.79 | FAAH (0.53) | GPR84FFAR1FFAR4ALDH1A1MEN1 | |
| SCHEMBL27778113 | 0.79 | FAAH (0.53) | GPR84FFAR1FFAR4ALDH1A1MEN1 | |
| SCHEMBL27518625 | 0.79 | FAAH (0.53) | GPR84FFAR1FFAR4ALDH1A1MEN1 | |
| SCHEMBL27499818 | 0.79 | FAAH (0.53) | GPR84FFAR1FFAR4ALDH1A1MEN1 | |
| SCHEMBL27499819 | 0.79 | FAAH (0.53) | GPR84FFAR1FFAR4ALDH1A1MEN1 | |
| SCHEMBL27545228 | 0.78 | FAAH (0.52) | GPR84FFAR1FFAR4ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073633-A2 | SUBSTITUTED BETA-AMINO ACID INHIBITORS OF METHIONINE AMINOPEPTIDASE-2 | ABBOTT LABORATORIES (US) | 2001-02-07 | — | — | EP | claimed |
| WO-1999057098-A2 | SUBSTITUTED BETA-AMINO ACID INHIBITORS OF METHIONINE AMINOPEPTIDASE-2 | ABBOTT LABORATORIES (US) | 1999-11-11 | — | — | WO | claimed |