Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 8/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MTTP | P55157 | 6/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7374117 | 0.90 | MEN1 (0.42) | GAAKDM4EPOLBMEN1KMT2A | |
| SCHEMBL7377885 | 0.88 | MTTP (0.43) | GAAKDM4EMTTPMEN1KMT2A | |
| SCHEMBL7375680 | 0.87 | MEN1 (0.41) | GAAKDM4EPOLBMEN1KMT2A | |
| SCHEMBL7373144 | 0.87 | MEN1 (0.41) | GAAKDM4EPOLBMEN1KMT2A | |
| SCHEMBL7373278 | 0.86 | MELK (0.45) | MCHR1GAAKDM4EMTTPHTT | |
| SCHEMBL7375925 | 0.85 | MTTP (0.40) | MCHR1GAAMTTPALDH1A1 | |
| SCHEMBL7376078 | 0.84 | AVPR2 (0.42) | MCHR1KDM4EMTTPALDH1A1HPGD | |
| SCHEMBL7375888 | 0.84 | POLB (0.44) | MCHR1GAAKDM4EMTTPHTT | |
| SCHEMBL7375063 | 0.83 | ALDH1A1 (0.36) | KDM4EMTTPMEN1KMT2AALDH1A1 | |
| SCHEMBL7373196 | 0.83 | MTTP (0.40) | KDM4EMTTPMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211242-B1 | CARDIOVASCULAR DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0757670-B1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-01-13 | — | — | EP | disclosed |
| WO-1995029152-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-02 | — | — | WO | disclosed |