Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 17/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | CA6 | P23280 | 2/20 | 0.43 |
| ▸ | CA5A | P35218 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7509681 | 1.00 | CA2 (0.46) | CA2CA1CA12CA4CA6 | |
| Hydrochloric Acid SCHEMBL9595874 | 0.93 | CA2 (0.48) | CA2CA1CA12CA4CA6 | |
| SCHEMBL7510985 | 0.92 | CA2 (0.49) | CA2CA1CA12CA4CA6 | |
| SCHEMBL7515912 | 0.92 | CA2 (0.49) | CA2CA1CA12CA4CA6 | |
| SCHEMBL7509743 | 0.92 | CA2 (0.51) | CA2CA1CA12CA4CA6 | |
| SCHEMBL7516791 | 0.91 | CA2 (0.49) | CA2CA1CA12CA4CA6 | |
| SCHEMBL7509361 | 0.91 | CA2 (0.49) | CA2CA1CA12CA4CA6 | |
| SCHEMBL7510317 | 0.88 | CA2 (0.55) | CA2CA1CA12CA4CA6 | |
| SCHEMBL7516535 | 0.88 | CA2 (0.55) | CA2CA1CA12CA4CA6 | |
| SCHEMBL7516790 | 0.88 | CA2 (0.43) | CA2CA1CA12CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527801-B1 | THIOPHENE SULFONAMIDES USEFUL AS CARBONIC ANHYDRASE INHIBITORS | ALCON LAB INC (US) | 2002-07-31 | — | — | EP | claimed |
| EP-0527801-A4 | THIOPHENE SULFONAMIDES USEFUL AS CARBONIC ANYDRASE INHIBITORS | — | 1993-03-10 | — | — | EP | claimed |
| EP-0527801-A4 | THIOPHENE SULFONAMIDES USEFUL AS CARBONIC ANYDRASE INHIBITORS | — | 1993-03-10 | — | — | EP | disclosed |