Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 4/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.37 |
| ▸ | FASN | P49327 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8053605 | 1.00 | TRPV4 (0.40) | TRPV4KDM1ACHEK1FASNAR | |
| SCHEMBL7736726 | 0.96 | TRPV4 (0.37) | TRPV4KDM1ACHEK1FASNAR | |
| SCHEMBL7736721 | 0.96 | TRPV4 (0.37) | TRPV4KDM1ACHEK1FASNAR | |
| SCHEMBL9828501 | 0.96 | TRPV4 (0.37) | TRPV4KDM1ACHEK1FASNAR | |
| SCHEMBL10524228 | 0.96 | TRPV4 (0.37) | TRPV4KDM1ACHEK1FASNAR | |
| SCHEMBL7736719 | 0.96 | TRPV4 (0.37) | TRPV4KDM1ACHEK1FASNAR | |
| SCHEMBL7736716 | 0.96 | TRPV4 (0.37) | TRPV4KDM1ACHEK1FASNAR | |
| SCHEMBL8973145 | 0.92 | TRPV4 (0.35) | TRPV4KDM1ACHEK1FASNAR | |
| SCHEMBL8973136 | 0.92 | TRPV4 (0.35) | TRPV4KDM1ACHEK1FASNAR | |
| SCHEMBL8973139 | 0.92 | TRPV4 (0.35) | TRPV4KDM1ACHEK1FASNAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0363451-B2 | SUPERTWIST LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 1999-12-15 | — | — | EP | claimed |
| US-4923632-A | LOW THRESHOLD-VOLTAGE AND TEMPERATURE DEPENDENCY; CYCLOHEXYL-AND FLUORO-SUBSTITUTED BENZENE | CHISSO CORPORATION (JP) | 1990-05-08 | — | — | US | claimed |
| US-10465114-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2019-11-05 | — | — | US | disclosed |
| US-9701905-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-07-11 | — | — | US | disclosed |
| US-9701905-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-07-11 | — | — | US | disclosed |
| US-20150315473-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-11-05 | — | — | US | disclosed |
| US-20150315473-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-11-05 | — | — | US | disclosed |
| US-20150299577-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-10-22 | — | — | US | disclosed |
| US-20150299577-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-10-22 | — | — | US | disclosed |
| EP-1116770-B1 | NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY USING THE SAME | DAINIPPON INK & CHEMICALS (JP) | 2008-04-02 | — | — | EP | disclosed |
| US-7198827-B1 | Nematic liquid crystal composition and liquid crystal display device using the same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2007-04-03 | — | — | US | disclosed |
| EP-0597701-A1 | Conjugated enyne derivative and liquid crystal composition | CHISSO CORPORATION (JP) | 1994-05-18 | — | — | EP | disclosed |
| EP-0318003-B1 | A liquid crystal composition for twist nematic mode | CHISSO CORP (JP) | 1993-10-20 | — | — | EP | disclosed |
| US-5102577-A | Supertwisted birefringence system | CHISSO CORPORATION (JP) | 1992-04-07 | — | — | US | disclosed |
| EP-0281065-B1 | LIQUID CRYSTAL COMPOSITION AND DISPLAY ELEMENT | CHISSO CORPORATION (JP) | 1991-11-27 | — | — | EP | disclosed |
| EP-0393636-A2 | Liquid crystal composition and liquid crystal display using said composition | CHISSO CORPORATION (JP) | 1990-10-24 | — | — | EP | disclosed |
| US-4923632-A | LOW THRESHOLD-VOLTAGE AND TEMPERATURE DEPENDENCY; CYCLOHEXYL-AND FLUORO-SUBSTITUTED BENZENE | CHISSO CORPORATION (JP) | 1990-05-08 | — | — | US | disclosed |
| US-4877549-A | HIGH MULTIPLEXING DISPLAY DEVICE | CHISSO CORPORATION (JP) | 1989-10-31 | — | — | US | disclosed |
| EP-0318003-A2 | A liquid crystal composition for twist nematic mode | CHISSO CORPORATION (JP) | 1989-05-31 | — | — | EP | disclosed |
| EP-0281065-A1 | Liquid crystal composition and display element | CHISSO CORPORATION (JP) | 1988-09-07 | — | — | EP | disclosed |