Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.34 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7509290 | 0.93 | MAP2 (0.39) | CHRNB2CHRNA4ALPLJAK2JAK1 | |
| SCHEMBL7507746 | 0.93 | HTR2A (0.35) | CHRNB2CHRNA4MAP4K4CHEK1CHRNB1 | |
| SCHEMBL7508487 | 0.91 | MAPK13 (0.38) | CHRNB2CHRNA4MAPK13MAPK12MAPK11 | |
| SCHEMBL7504471 | 0.90 | CHRNB2 (0.35) | CHRNB2CHRNA4CHEK1TGFBR1CHRNB1 | |
| SCHEMBL7502638 | 0.90 | HTR2A (0.39) | CHRNB2CHRNA4CHEK1 | |
| SCHEMBL7508483 | 0.89 | CDK7 (0.37) | CHEK1PDPK1RPS6KB1TGFBR1CYP11B1 | |
| SCHEMBL7507840 | 0.87 | KCNH2 (0.35) | CHRNB2CHRNA4MAPK13MAPK12MAPK11 | |
| SCHEMBL7508903 | 0.85 | CDK7 (0.41) | CHRNB2CHRNA4CHEK1 | |
| SCHEMBL7503822 | 0.85 | CYP2A6 (0.36) | CHRNB2CHRNA4CHEK1PDPK1RPS6KB1 | |
| SCHEMBL7502243 | 0.84 | MAPK13 (0.38) | CHRNB2CHRNA4MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634408-B1 | DEPSIPEPTIDE DERIVATIVE, PRODUCTION THEREOF AND USE THEREOF | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-01-02 | — | — | EP | disclosed |
| EP-0634408-A1 | DEPSIPEPTIDE DERIVATIVE, PRODUCTION THEREOF AND USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-01-18 | — | — | EP | disclosed |