Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7860321 | 1.00 | BCHE (0.34) | BCHEALDH1A1KDM4EPKMHSD17B10 | |
| SCHEMBL8873316 | 0.81 | SMN1; SMN2 (0.46) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL16433822 | 0.76 | CHRM2 (0.39) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL16433770 | 0.76 | CHRM2 (0.39) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL9148812 | 0.75 | TSHR (0.36) | KDM4ESMN1; SMN2 | |
| SCHEMBL9148823 | 0.75 | TSHR (0.36) | KDM4ESMN1; SMN2 | |
| SCHEMBL9148809 | 0.75 | TSHR (0.36) | KDM4ESMN1; SMN2 | |
| SCHEMBL9370493 | 0.72 | SMN1; SMN2 (0.47) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7515881 | 0.69 | HPGD (0.30) | — | |
| SCHEMBL15657075 | 0.69 | SMN1; SMN2 (0.42) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0585328-B1 | SUBSTITUTED 3-AMINOQUINUCLIDINES | PFIZER (US) | 2002-01-09 | — | — | EP | disclosed |
| US-5852038-A | Substituted 3-aminoquinuclidines | PFIZER INC (US) | 1998-12-22 | — | — | US | disclosed |
| US-5716965-A | Substituted 3-aminoquinuclidines | PFIZER INC. (US) | 1998-02-10 | — | — | US | disclosed |
| EP-0585328-A1 | SUBSTITUTED 3-AMINOQUINUCLIDINES | PFIZER INC. (US) | 1994-03-09 | — | — | EP | disclosed |
| WO-1992020676-A1 | SUBSTITUTED 3-AMINOQUINUCLIDINES | PFIZER INC. (US) | 1992-11-26 | — | — | WO | disclosed |