SCHEMBL7515904

SCHEMBL7515904

C=C(C(=O)Oc1ccccc1)P(=O)(c1ccccc1)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.42
TDP1 Q9NUW8 3/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
SRC P12931 1/20 0.38
ATM Q13315 2/20 0.38
CA2 P00918 1/20 0.38
CA4 P22748 1/20 0.38
CA5A P35218 1/20 0.38
ALOX15 P16050 2/20 0.37
HPGD P15428 1/20 0.37
HSD17B10 Q99714 1/20 0.37
MAPT P10636 3/20 0.37
ALDH1A1 P00352 1/20 0.37
TSHR P16473 1/20 0.36
USP2 O75604 1/20 0.36
RAD51 Q06609 1/20 0.36
PTK2B Q14289 1/20 0.36
NPSR1 Q6W5P4 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29421945 0.78 CA2 (0.52) TDP1L3MBTL1CA2CA4CA5A
SCHEMBL8003558 0.77 CA2 (0.46) TDP1L3MBTL1CA2CA4CA5A
SCHEMBL7515897 0.76 ELANE (0.41) ELANETDP1L3MBTL1SRCATM
SCHEMBL27505259 0.75 ELANE (0.49) ELANETDP1L3MBTL1ATMALOX15
SCHEMBL6658962 0.74 ELANE (0.52) ELANETDP1L3MBTL1ATMALOX15
SCHEMBL5132602 0.74 ELANE (0.52) ELANETDP1L3MBTL1ATMALOX15
Diphenyl Ethanedioat SCHEMBL43364 0.73 TDP1 (0.54) ELANETDP1L3MBTL1SRCATM
SCHEMBL28830577 0.73 MAPT (0.43) TDP1L3MBTL1CA2CA4CA5A
Phosphoric Acid SCHEMBL15355415 0.73 ELANE (0.65) ELANETDP1L3MBTL1SRCATM
Phosphoric Acid SCHEMBL28493167 0.73 ELANE (0.65) ELANETDP1L3MBTL1SRCATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6399731-B2 SYNTHESIZING POLYMERS USING PHOSPHOROUS-CONTAINING ADDITION-FRAGMENTATION CHAIN TRANSFER AGENTS; MOLECULAR WEIGHT CONTROL THE UNIVERSITY OF AKRON 2002-06-04 US disclosed
US-20020016424-A1 Synthesizing polymers using phosphorous-containing addition-fragmentation chain transfer agents; molecular weight control AKRON, THE UNIVERSITY OF 2002-02-07 US disclosed