Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7523505 | 0.83 | RAB9A (0.46) | KMT2AMAPTMEN1RAB9AEPHX1 | |
| SCHEMBL8245794 | 0.76 | RAB9A (0.44) | KMT2AMAPTMEN1RAB9AEPHX1 | |
| SCHEMBL7573500 | 0.75 | NPC1 (0.47) | KMT2AMAPTMEN1RAB9AEPHX1 | |
| SCHEMBL7518027 | 0.74 | RAB9A (0.45) | KMT2AMAPTMEN1RAB9AEPHX1 | |
| SCHEMBL7521701 | 0.70 | EPHX2 (0.42) | KMT2AMAPTMEN1RAB9AEPHX1 | |
| SCHEMBL9374987 | 0.69 | APEX1 (0.71) | KMT2AMEN1TSHR | |
| SCHEMBL7523145 | 0.69 | EPHX2 (0.51) | KMT2AMEN1RAB9AEPHX1EPHX2 | |
| SCHEMBL29838164 | 0.69 | APEX1 (0.71) | KMT2AMEN1TSHR | |
| SCHEMBL7521127 | 0.68 | NPC1 (0.52) | KMT2AMAPTMEN1EPHX1EPHX2 | |
| SCHEMBL7524471 | 0.68 | EPHX2 (0.41) | KMT2AMAPTMEN1RAB9AEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173420-A2 | HETEROCYCLIC COMPOUNDS HAVING ANTITUMOR ACTIVITY | Novuspharma S.p.A. (IT) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000053581-A2 | HETEROCYCLIC COMPOUNDS HAVING ANTITUMOR ACTIVITY | NOVUSPHARMA S.P.A. (IT) | 2000-09-14 | — | — | WO | disclosed |