Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA9 | Q16790 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7516086 | 1.00 | CA2 (0.46) | CA2CA9CA1CA7KMT2A | |
| SCHEMBL11406841 | 0.83 | SIRT2 (0.67) | CA2CA9CA1CA7KMT2A | |
| SCHEMBL11406860 | 0.83 | SIRT2 (0.67) | CA2CA9CA1CA7KMT2A | |
| SCHEMBL7514609 | 0.81 | SIRT2 (0.58) | CA2CA9CA1CA7KMT2A | |
| SCHEMBL7514613 | 0.81 | SIRT2 (0.58) | CA2CA9CA1CA7KMT2A | |
| SCHEMBL27599235 | 0.80 | SIRT2 (0.50) | CA2CA9CA1CA7KMT2A | |
| 3-(Benzylideneamino)Phenol SCHEMBL5230991 | 0.75 | PTGS1 (0.50) | CA2CA9CA1CA7KMT2A | |
| 3-(Benzylideneamino)Phenol SCHEMBL5230984 | 0.75 | PTGS1 (0.50) | CA2CA9CA1CA7KMT2A | |
| SCHEMBL11418963 | 0.73 | SIRT2 (0.62) | CA2CA9CA1CA7KMT2A | |
| SCHEMBL11418959 | 0.73 | SIRT2 (0.62) | CA2CA9CA1CA7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020032262-A1 | 2-aminoarylmethylamine solid support templated for preparation of highly functionalized heterocycle compounds | ZHANG JINFANG (US) | 2002-03-14 | — | — | US | disclosed |